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Musculoskeletal disorders (MSDs) are the most common work-related health problem among the non ergonomic work posture in work station design. Tailors at PT. Uluwatu Delod Peken Village, Tabanan District, Tabanan Regency are one many occupation that have risk of MSDs. The aim of this study was to find out the correlation between sitting posture with MSDs. The amount of the sample was 40 tailors involved in this study. Musculoskeletal disorders were measured using Nordic Body Map Questionnaire with Likert scale. While working posture was observed in Rapid Entire Body Assessment (REBA) Employee Assessment Worksheet. The data was analyzed by SPSS.23. The results of MSDs were as follow the light, the mild, heavy category, 25%, 42,5%, 32,5% respectively. The working posture were as follow ergonomic approach with low risk (22,5%) and non ergonomic with medium risk (77,5%). The correlation of both variables above was significant (p<0.05). The conclusion could be drawn that there was correlation between work posture with MSDs. It was recommended that the work posture of the tailors should be improved to reduce the risk of suffered MSDs.