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International Classification of Functioning, Disability and Health (ICF) defines disability as a general term for disruption, restrictions on activities and restrictions on participation. Disability causes an individual to experience deterioration in health, problems with his own personality (negative attitude), and the environment (limited social support and difficult access). More than one billion people are estimated to live with various types of disabilities. There are around 15% of the world population which is 110 million (2.2%) and 190 million (3.8%) people aged 15 years and over have difficulties in performing their functions. The purpose of this study was to determine the characteristics and prevalence of children with disabilities in SLB students in West Sulawesi Province. The design of this study was cross sectional with a descriptive approach. The study population was 1392. Study results of the characteristics of persons with disabilities in West Sulawesi Province SLB students were 58.33% male and 41.66% female, 32.03% at the age of 19 years, and the most types of disabilities namely mentally disabled as much as 60.44%. Percentage of occurrence Overweight in West Sulawesi province SLB students was 1.74%.