The Effectiveness of Durian Skin Extract as a Natural Anti-Bacterial Nina Arlofa, Ismiyati, Moh. Kosasih
Chemical Engineering Masters Program, Faculty of Engineering, Muhammadiyah Jakarta, Indonesia
Abstract
Durian (durio zibertinus) is a native tropical fruit from Southeast Asia, especially in Indonesia. Durian skin is the highest composition of durian fruit (60-75%), but still considered as waste that caused environmental problems. Durian skin was extracted with ethanol to obtain the extract which is then separated from the solvent as an ingredient for the hand sanitizer formula. This study aims to analyze the content of secondary metabolites of durian skin extract, analyze the anti-bacterial activity of durian skin extract against gram-negative and gram-positive bacteria and calculate the effectiveness of durian skin extract as a natural anti-bacterial ingredient in hand sanitizer products by using the paper disc method. The results showed that durian skin extract contained triterpenoids, alkaloids, and saponins, which are phytochemical compounds that have anti-bacterial function. The concentration of 1% durian skin extract inhibited the growth of Escersia coli, Salmonela thyposa and Sthapylococcus aureus with a clear zone of 8.2 mm, 7.4 mm and 8.6 mm, respectively. In the anti-septic test, the hand sanitizer showed that the interaction between the concentration of durian skin extract and the time interval of sampling at the same time (simultaneously) gave a significant effect in reducing the number of microorganism colonies
Keywords: natural anti-bacterial, Durian skin, hand sanitizer
Topic: International Symposium of Engineering, Technology, and Health Sciences
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