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Oocyte maturation rate is an important factor in determining a good fertilization and embryo development rate with in vitro fertilization. Embryos that can develop until blastocyst stage have been proven to have a higher success rate than cleavage stage embryos. The aim of this study is to find out effect of age and body mass index (BMI) in oocyte maturation rate and the successfulness of blastocyst development. In this study, 158 infertile women within age range of 22-47 who underwent IVF-ICSI program in Halim Fertility Center were analyzed. The IVF-ICSI outcomes assessed were number of oocytes retrieved (OR), number of matured oocytes (MO), fertilization rates (FR), cleave rates (CR), the blastocyst rates (BR), and the pregnancy rates (PR). All data were divided into three groups based on WHO BMI classification (normal range, overweight and obese) and four groups based on age classification (up to 30, 31-35, 36-40, below 41). These data were analyzed with student T test method and chi-square. In result, our study concludes that the body mass index shows a negative effect of oocyte maturation process and blastocyst development. However, age had an adverse impact on number of oocyte retrieved, number of matured oocyte, and blastocyst rates.