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Etching process in orthodontic treatment and the process of debonding orthodontic brackets often cause damage around the enamel surface. Novamin is a synthetic mineral that has a similar mineral structure contained in a tooth, so this study aims to determine the potential of Novamin as a remineralization material in terms of the content of Ca, O, P and enamel surface. Expected to improve enamel damage after orthodontic treatment. Twenty-five premolar teeth were divided into five groups. Group I (control), II (etching and bracket mounting with biofix), III (same as group II + Novamin), IV (etching and bracket mounting with Fuji Ortho LC), and V (same as group IV + Novamin). The polymerization process with LEDs is 20 seconds. All samples are placed in artificial saliva for seven days. The bracket is removed and cleaning the remaining adhesive material. Novamin application for 3 minutes every 12 hours for ten days. Chemical composition was analyzed by EDX analysis and enamel surface changes by Scanning Electron Microscope. There were significant differences in the content of Ca elements in groups I, II, III, and V (p0,05), while P in all groups (p 0,05). Changes to the surface of the enamel indicate the existence of open enamel prisma, pits and grooves. Conclusion: Novamin can do remineralization after orthodontic brackets removal as seen from the levels of Ca and P elements, as well as the surface description of the enamel