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This paper discusses about the issues in producing of collagen-like protein. In this digital era, it is stated that there are existing challenges in production of Halal recombinant collagen-like protein. Initially, a number of collagen-like proteins have been recognised in bacteria during the last ten years, plenty of challenges are identified. The objective of this paper solved the challenges of recombinant collagen-like protein to overcome the high demands of collagen in this digital era, limited supplies of collagen alternative, difficulty in addressing the post-translational modification of recombinant human collagen and the Halal certification of the material itself. It relies on inductive methodology to collect the Qur-anic verses as well as Hadith that related to face the challenges of recombinant collagen-like protein and the analytical method to analyse Qur-anic verses and Sunnah associated with this subject. The findings may also provide better understanding towards issues of Halal policy on recombinant collagen-like protein acceptance on the concept.