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Abstract. This study aims at investigating whether the implementation of “course system horay” is able to boost the students- outcome and their interest in the subject of general biology, odd semester of the 2019/2020 academic year. The type of this study is categorized as classroom action research with 50 students as the subject research. The data collection was conducted using observation, questionnaires, paper-based test and documentation. Meanwhile, the technique of analysis was done using descriptive study. By implementing course system horay, we report that there is a significant increase in the students- outcome in the general biology course. The analysis also reveals that the mean scores of students- interest is higher on average.