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Background: Breast cancer is the second leading cause of death in women after cervical cancer, but breast cancer can be prevented by reducing risk factors. This study aims to determine the effect of health education through audio visual on women childbearing ages knowledge and attitudes about preventing of breast cancer. Methodology: This study uses the method quasy experiment with pre-post test with control group. The number of respondents was 62, divided into 31 respondents of control group and 31 respondents of intervention group 31. The research Instrument used a questionnaire. The data were examined using Paired t-test, Wilcoxon, Independent t-test and Mann-Whitney. Research Results: The statistical test results showed that there were significant differences in the posttest knowledge between the control group and the intervention group (p= 0.001). The results of statistical tests on attitudes variables showed that there were significant differences in the posttest between control group and intervention group (p= 0.003). Conclusion: Health education through audio visual could significantly improves the women childbearing ages knowledge and attitude about prevention of breast cancer