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Background: Majority mortality cases in Intensive Care Unit (ICU) happen after decision making. Nurses as an inseparable part of End of Life decision making in ICU have unique experience and condition as lived experience. Understanding Muslim nurses- lived experience can provide insights for increase quality of care during End of Life decision making in ICU. Muslim nurses- thoughts and feelings while delivering care in EOL decision making have not been described and understood. This study was conducted to described the meaning of Muslim nurses- lived experience in involvement at the EOL decision making in ICU. Purpose: To describe the meaning of the lived experience of Muslim nurses during their involvement in End of Life decision making in ICU. Methods: Hermeneutic phenomenological study was used to underpin this study. Fourteen nurses who work in ICU in Indonesia met the inclusion criteria: Muslim nurses and have been working in ICU for at least 3 years. Data were collected using in-depth individual interviews. Data transcription were analyzed by using van Manen-s hermeneutic phenomenological approach. Lincoln and Guba-s criteria were followed to established trustworthiness. Results: Four major thematic categories reflecting the four life worlds were identified: “feeling dilemma”, “being in uncertain time”, receiving overwhelming role”, and “evade from the process”. Conclusion: This study provides further knowledge regarding the meanings of the lived experience of Muslim nurses during their involvement in End of Life Decision making in ICU.