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Background : Postoperative Sore Throat (POST) is a side effect of the intubation that can cause difficulty in swallowing and breathing. Late treated POST can prolong the recovery period and reduce the patients satisfaction. Cold compress and guided imagery is a non-pharmacological method that can be applied to treat pain. This study aims to determine the effectiveness of cold compress and guided imagery to reduce the pain scale of POST. Methodology : The research design used quasi experiment pre-post test with two groups design using purposive sampling with 60 respondents divided into two groups, 30 cold compress groups and 30 respondents as the guided imagery groups. Instrument using a Numeric Rating Scale (NRS). Data analysis test used paired t test and independent t test. Research result: There were significant differences between the pain scale before and after the intervention of cold compress (p 0.001) and guided imagery (p 0.001). There was not significant differences between the two groups to reduce the pain scale of POST (p 0.166). Conclusion : Cold compress and Guided imagery are both effective in reducing the pain scale of POST.