Indonesia Conference Directory

Abstract Objective: The aim of this study was to determine the effectiveness of topically administered corn silk extract to reduce blood glucose level and its effect on hyperglycemic related periodontal tissue inflammation. Method: Fifteen male Wistar rats with an initial weight of 150 gram were included in this study. Alloxan was used to induce diabetes and 5-0 silk ligatures to induce periodontal tissue inflammation. Blood glucose level was analyzed before and after induction, 3 days and 7 days after administration. Degree of periodontal tissue inflammation was examined with the histopathology test. Statistical analysis was conducted using the student t-test. Results: Blood glucose level in F1 group was unstable (p=0.0583>p=0.05), whilst both F2 and F3 group showed stable blood glucose decrease (F2: p=0.0086p=0.05; F2: p=0.423>p=0.05). Conclusion: Topically administered corn silk extract was effective to reduce blood glucose level and hyperglycemic related periodontal tissue inflammation in alloxan-induced diabetic rats