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ABSTRACT Bangkal stem bark (N. subdita) contains secondary metabolite compounds from polyphenols such as flavonoids, saponins, steroids, and tannins which have the potential as natural antioxidants. Antioxidants have a function to protect the body from the bad effects of free radicals that can cause skin damage. This study aimed to determine the IC50 value of methanolic extracts of Bangkal stem bark before being formulated with after being formulated into antioxidant lotions and to determine effect of emulgator concentration to antioxidant activity of lotion. In this study lotion was formulated with different concentration of stearic acid : FI (2%), F2 (3%) & FII (5%). Determination of antioxidant activity was carried out using the DPPH method and ascorbic acid as a comparison. The result of IC50 value of methanolic extract of N. subdita stem bark is 34.1787 ± 0.2781 ppm, which is classified as a very active antioxidant. The result shows that the increase of stearic acid concentration affect the antioxidant activity, the higher concentration of stearic acid, the greater IC50 value. The results for lotions FI,FII& FIII IC50 value are 61.5593 ± 0.2673 ppm, 66.8051 ± 0.2317 ppm & 72.6253 ± 2.3117 ppm, respectively. All formulas have IC50 range 50-100 ppm which are classified as active antioxidants. Based on the research it can be conclude that the methanolic extract of N. subdita stem bark has a very active antioxidant activity and the lotions classified as active antioxidant. Keywords : Antioxidant, Lotion, Emulgator, Bangkal (Nauclea subdita) ABSTRAK Kulit batang bangka (N. subdita) mengandung senyawa metabolit sekunder dari golongan polifenol seperti flavonoid, saponin, steroid, dan tanin yang berpotensi sebagai antioksidan alami. Antioksidan memiliki fungsi untuk melindungi tubuh dari pengaruh buruk radikal bebas yang dapat menyebabkan kerusakan kulit. Penelitian ini bertujuan untuk menentukan nilai IC50 ekstrak metanol kulit batang bangkal sebelum diformulasikan dengan sesudah diformulasikan menjadi lotion antioksidan dan menentukan pengaruh konsentrasi emulgator terhadap aktivitas antioksidan lotion. Dalam penelitian ini lotion diformulasikan dengan variasi konsentrasi asam stearat yaitu FI (2%), F2 (3%) & FII (5%). Penentuan aktivitas antioksidan dilakukan menggunakan metode DPPH dan asam askorbat sebagai pembanding. Hasil nilai IC50 ekstrak metanol kulit batang N. subdita yaitu 34,1787 ± 0,2781 yang tergolong sebagai antioksidan sangat aktif. Hasil peneltian menunjukkan peningkatan konsentrasi asam stearat mempengaruhi aktivitas antioksidan, semakin tinggi konsentrasi asam stearat semakin besar nilai IC50. Hasil IC50 lotion pada FI, FII & FII berturut-turut 61,5593±0,2673 ppm, 66,8051 ± 0,2317 ppm & 72,6253 ± 2,3117 ppm. Ketiga formula memiliki rentang nilai IC50 50-100 ppm yang tergolong sebagai antioksidan aktif. Berdasarkan penelitian dapat disimpulkan bahwa ekstrak metanol kulit batang N. subdita