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Nowadays, the success of an organization depends heavily on employees- productivity which can be influenced by employees- health conditions. Generally, either an organization or individual need hospital for health services. This has an impact on the growth of hospitals which continues to increase, so that competition in the health industry will be even higher. Therefore health industry stakeholders require to continue improving their services, either through improved facilities or improvements from the employees- side. Based on research, turnover intention is one of many problems which must be solved by health industry stakeholders. Many factors can influence turnover intention, i.e. workplace spirituality, perceived organizational support, and organizational commitment. The purpose of this study was to know the effects of these factors on turnover intention mediated by organizational commitment. A total of 235 employees from private hospital in Jakarta participated as respondents. Data obtained through questionnaires and then analyzed using SEM. The results showed that organizational commitment was positively influenced by perceived organizational support and workplace spirituality. Furthermore, workplace spirituality and organizational commitment negatively affected turnover intention. Organizational commitment can mediate the relationship between workplace spirituality and turnover intention.