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Slatri leaves (Calophyllum soulattri) which contains flavonoids, tanin, xhantone, and cumarin, has potential as an antioxidant. This research objective is to find antioxidant activity and total flavonoid total extract and fraction of slatri leaves. This research was conducted with laboratory experimental methods which include antioxidant activity assay using DPPH (2,2-diphenyl-1-pikrilhidrazil) is determined by the amount of DPPH radical absorption barriers represented by IC50. Levels of total flavonoids was determined by colorimetric method with AlCl3 reagent routinely expressed as a percentage in the extract. The results showed IC50 leave ethanol extract against DPPH with slatri of 39.63 ± 14.99 ppm and total flavonoid content of leaf extracts slatri of 25.677 ± 0.046% in the extract routine