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The level of cleanliness, difficulty access to clean water, and population density of dwellings are factors that influence high incidence of scabies in developing countries. One factor contributing to the incidence of scabies especially in Islamic Boarding School are clean and healthy living behavior education programs. can protect and avoid scabies in Islamic boarding schools. Based on that, this study aims to compare method on clean and healthy living behavior by tutorials and providing a "Healthy Santri Pocket Book”. This study was a quasi-experiment with pre and post test approach. The results showed that tutorias the Pre-Test: 89.24, Post-Test Scabies: 89,26. While providing Healthy Santri Pocket Book Pre-Test : 76,89 Post-Test : 89,63. From these results, the better method in increasing students knowledge is through the Healthy Santri Pocketbook.