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Goosegrass (Eleusine indica) is an important weed in rubber plantation. It is getting more difficult to control with glyphosate herbicide of which is normally very common used to control the weed in rubber plantation in North Sumatra. The objective of the study was to evaluate the efficacy of preemergent (indaziflam 150g a.i/ha) and postemergent herbicides (glyphosate 720g a.e./ha, paraquat 400g a.i/ha, ammonium glufosinate 450g a.i./ha) alone or mixtures (glyphosate 720g a.i + metsulfuron methyl 15g a.i./ha, glyphosate 720g a.e./ha + 100g indaziflam a.i/ha) on goosegrass growing on the rubber field along the rubber row. Apart from those treatments there were plots cleared by scrapping the soil surface and plot without treatment. The results showed that indaziflam at 150g/ha and 720 g a.e glyphosate /ha + 100g indaziflam/ha) and manually only cleared controlled the goosegrass effectively followed by 450 g a.i ammonium glufosinate /ha whereas paraquat at 400g.a.i/ha and glyphosate at 720 g a.e/ha either alone or mixture with metsulfuron methyl at 15 g a.i/ha did not control goosegrass satisfactorily