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Background: Cognitive impairment related to cancer is often known as cancer related cognitive impairment (CRCI) and gained attention from researchers due to its subtle etiology and its effect on quality of life and well-being in cancer patient. Purpose: This study reviews published articles in order to examine the prevalence of cognitive impairment, affected cognitive domain, identify the relationship between objective and subjective cognitive impairment and to explore the associated factors that influence subjective cognitive impairment in breast cancer patient. Methods: A systematic and comprehensive search using combination of keywords on four electronic databases (CINAHL, Cochrane Library, Science Direct and PubMeD) and from references list. Findings: 36 articles were selected and represent 5537 patients. The studies demonstrated that the prevalence of subjective cognitive impairment (11% to 95%) was higher than objective cognitive impairment (1.4% to 65%). Only 17 studies measure the relationship between objective and subjective cognitive impairment, seven studies indicate low correlation and the remaining ten studies showed no correlation. Memory was the most affected domain in cognitive function. Subjective cognitive impairment was more likely to be associated with depression, fatigue and anxiety. Conclusion: The influence of emotional disturbance and physical weakness may have a significant impact on higher prevalence of subjective cognitive impairment. It is important to acknowledge all aspects correlated with cognitive impairment due to its influence on wellness, quality of life and survivorship trajectory of breast cancer patients.