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HIV infection is closely related to nutrition. Decreasing food intake and nutritional status in people with HIV-AIDS is multifactorial. Diet therapy and nutritional knowledge play an important role in healing HIV-AIDS. The purpose of this study is to determine the relationship between nutritional knowledge and attitudes toward food intake and nutritional status of people with HIV-AIDS. This study is an observational study with a cross sectional design in 45 people with HIV-AIDS. Nutritional knowledge and attitudes are collected by interview using a questionnaire. Food intake (energy, protein, fat and carbohydrate) is collected by interview using SQFFQ. Nutritional status is obtained from measurements of body weight and height and then BMI calculation is performed. The statistical analysis used is the chi square test. There is a significant relationship between knowledge and energy intake (p<0.05) and there is no significant relationship between knowledge with protein, fat and carbohydrate intake (p>0.05). There is no significant relationship between attitude and food intake (p>0.05). There is no significant relationship between knowledge and attitude with nutritional status (p>0.05). Low nutritional knowledge risks of experiencing low energy intake and 2.8 times suffering from malnutrition