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Background: Typhoid fever is an acute disease in the community caused by Salmonella typhi bacteria. How to spread the bacteria through oral-fecal with the intermediary of contaminated water and cooking. There are still many people in Indonesia who do not care about environmental cleanliness, especially in densely populated Jakarta. Varied clinical symptoms that make diagnosis difficult as well as laboratory results. So that research needs to be done to detect clinical symptoms or laboratory tests that are commonly found in typhoid fever patients today. Objective: To know the description of clinical symptoms, laboratory in adults with typhoid fever in the January-March period 2018. Methods: The type of this study was a retrospective descriptive study, using a cross sectional study design with a total sample of 84 medical records of patients. The study was conducted from October-December 2018 at Hospital X, East Jakarta. Retrieval of data obtained from the patients medical record. Results: Adult typhoid patients were hospitalized in Hospital X, East Jakarta, 32.24% aged 19-24 years, 58.33% female, and length of stay for 3 days was 40.48% with an average of 3.06 days. Patients who have a fever of 92.86%. Examination of widal O titer 1/320 positive at 34.52% and H titre 1/160 positive at 21.43%, normal Hb at 54.76%, normal leukocytes at 50%, normal platelets at 77.39%. Conclusion: Typhoid sufferers often occur in young adults, some patients have anemia