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Background: Intradialytic complications are commonly experienced in hemodialysis patients. Haemodialysis patients usually gain weight between two dialysis time (interdialytic weight gain=IDWG). Patients who experience an increase in IDWG are associated with the incidence of intradialytic complications, such as hypotension, muscle cramps, hypertension, chest pain, headache, fever, nausea and vomiting. Objectives: To analyze the correlation between intradialytic complications and IDWG. Methods: This study used an observational analysis method with a cross-sectional design. Sample were recruited by using simple random sampling as and there were 56 samples on inclusion criteria. Data were analysed using Pearson product moment with significance level α≤0.05. Research ethics was obtained from Margono Soekarjo Hospital Results : The results showed that highest IDWG is 6.58% and the lowest is 0.62%. There was correlation between interdialytic weight gain (IDWG) and intradialysis complications (p=0.00 and r=0.443). Conclusion: It can be concluded that there was correlation between IDWG and intradialytic complications in patients undergoing a haemodialysis treatment at RSUD Prof. Dr Margono Soekarjo Purwokerto.