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Generally maintenance of ducks used wet system. The cage equipped with pool for bathing, drinking, reproducing and doing activities. However, this condition is not efficient in the limited land area. This research tried to implement dry systems. This system suppresses feed convertion, simplifies egg collection when ducks enter the layer period and makes it easy to manage. The weakness of this dry system can cause stress to ducks because minimal maintenance of water is contrary to the bodys function of ducks as waterfowl and causes oxidative stress. This study aims to produce a natural isotonic made from a mixture of celery extract and lime juice for local ducks that are intensively reared with a dry maintenance system and are able to reduce oxidative stress, with the right dosage indicated by blood hematology parameters as a picture of duck health. The results showed a significant decrease in leukocyte and platelet levels in T2 which is consist of 7% sugar + lime juice 3% + Celery extract 50 mg + salt 0.9gr. Hematocrit, hemoglobin, and erythrocyte levels also showed a decrease in T2 but were not significant. Decreased leukocyte levels at T2 indicate that the use of natural isotonic at these levels has an impact on increasing immunity to local ducks.