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Virtual Reality (VR) is a technology that has been widely used for various industrial purposes in recent days. Despite the potential benefits, VR usage may impose adverse effects that can prevent users reaching their goals of using VR safely and comfortably. One potential adverse effect is the disruption of the postural stability during VR usage. This study aimed to evaluate the effect of using VR on postural stability. A number of 14 participants involved in the experimental set up playing a simulated game with Samsung Gear Head Mounted Display (HMD) for 30 minutes with standing posture. During the experiment, center of pressure (COP) data were obtained every 10 minutes using an AMTI® forceplate to calculate postural stability using three parameters including mean distance (MD), mean velocity (MV), and sway area (SA). The results showed that longer duration of VR usage significantly increased MD and SA. Meanwhile, MV remained constant throughout the experiment. These indicated the use of VR may worsen users postural stability. Thus, caution should be used to develop future guideline to increase VR safety.