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Abstract. Micro Small and Medium Enterprises are one business model with small to medium capital. Money turnover in the Small and Medium Micro Enterprises business is quite fast, because generally they do retail business. The selling price of the product and its quality compete with each other, therefore a proper strategy is needed so that they can still get added profits. One way is to optimize the production process by maximizing profits. By taking a case study on the Micro Small and Medium Enterprises business that produces clothing, profits can be increased through operational optimization of production processes using linear programming and sensitivity analysis. From the results of the sensitivity analysis, an increase in the value of profits was obtained from 24% to 33%. The contribution of this research is to micro small and medium enterprises in the garment industry, it can be applied to be able to make plans to increase profits.