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Background: Stroke is the leading cause of long-term physical disability in Singapore, accounting for 6.1% of Disability-Adjusted Life Years. Despite the positive outcomes associated with stroke rehabilitation, only 33.3% of eligible stroke patients in Singapore use this service when referred. Purpose: We identified caregiver profiles based on their psychosocial needs, characterized profile movements over time, and investigated if these profiles differentiated patient-users of stroke rehabilitation from non-users. Methods: The full dataset comprises 378 patients who suffered from a recent stroke and their family caregivers, who completed measures of caregiver psychosocial need (burden, depression, health status, social support, social activities and relationship quality with patient) at baseline, 3-month and 12-month post-stroke. Latent profile analyses (LPAs) were conducted at each time point. Model fit indicators, entropy and the interpretability of competing solutions were considered when selecting an optimal profile solution. A latent transition analysis (LTA) was conducted with the optimal profile solution to characterize movements of latent profiles over time. Associations between caregivers- profile membership and patients- rehabilitation use over time were examined in a structural equation, with other caregiver and patient characteristics as covariates. Results: A two-profile solution, which comprises more adaptive caregivers (80.7% at baseline, 76.7% at 3-month and 87.4% at 12-month) and less adaptive caregivers, was selected. 31% of the less adaptive caregivers at baseline remained less adaptive at 12-month post-stroke (β = 2.15, p < .05). After controlling for covariates, the patients of more adaptive caregivers had 21.67 times higher odds of using, rather than not using, stroke rehabilitation (β = 2.64, p < .01) at 12-month post-stroke. Conclusion: Caregiver psychosocial need profiles differentiated longer-term stroke rehabilitation users from non-users. To increase patients- stroke rehabilitation use, direct caregiver psychosocial intervention should be provided at or before patients- discharge from acute hospital, and continue into the longer-term.