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Magnesium and its alloy are known as biodegradable materials. Application of these materials especially as an implant materials such as fracture fixation, cardiovascular stent and musculoskeletal. Characteristic modifications of these materials have been extensively done by some treatments. The objective of this paper is to review some treatments of the magnesium and its alloy to increase their characteristic as a biomaterial. In this paper, the treatment of magnesium and its alloy by coating, surface mechanical attrition treatment (SMAT), shot peening and thermal oxidation was reviewed. Some properties were studied base on these treatments such as corrosion resistant, morphology, wettability, and biocompatibility. Coating treatment by calcium phosphate was developed for orthopedic application. SMAT resulted in grain size of nanometer in the topmost surface of magnesium. Surface roughness and wettability also increased on the SMATed specimen but its corrosion resistant decreased. Severe shot peening on magnesium for orthopedic application should be studied intensively. Thermal oxidation of magnesium alloy improved both wear and corrosion resistant.