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Objective: To analyze the comparison of the principles of hospital governance on the performance of human resources at RSUD Labuang Baji and Ibnu Sina Hospital. Methods: The type of research used is explanatory research. The population in this study were all employees in the general section of RSUD Labuang Baji and Ibnu Sina Hospital. The number of samples was 76 employees. The sampling technique used exhaustive sampling. Results: Transparency (t: 0.833; Sig: 0.412), Accountability (t: -0.680; Sig: 0.502), and Independence (t: -0.889; Sig: 0.376) were not significant effect but Responsibility (t: 2,676; Sig: 0,012) and Fairness (t: 2,412; Sig: 0,022) were significant on performance in RSUD Labuang Baji. In Ibnu Sina Hospital, Transparency (t: -0.539; Sig: 0.594), responsibility (t: 1,545; Sig: 0,131) and Independency (t: -0.522; Sig: 0.605) were not significant effect , but accountability (t: 1.919; Sig: 0.063) and Fairness (t: 1,755; Sig: 0,088) fairness were influence but not significant on performance. Conclusion: Responsibility and fairness were variable that influences hospital governance on performance in RSUD Labuang Baji, while accountability and fairness were influence but not significant variables in Ibnu Sina Hospital.