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Relationship between Improve Lung Function with Decrease of Eosinophil Levels in Atopic Asthma Persistent After Asthma Exercise
Rahmaya Nova Handayani1, Faisal Yunus2, Ermita Isfandiary Ibrahim3 Iris Rengganis4

Doctoral Program in Biomedical Science, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Bachelor of Nursing Studies Program Universitas Harapan Bangsa Indonesia1,,Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia2; Department of Medical Physiology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia3; Department of Internal Medicine, Faculty of Medicine Universitas Indonesia Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia4


Abstract

Background: Asthma is a chronic inflammation that is a serious health problem in the world, especially in developing countries, one of which is characterized by limited expiratory air flow. Expiratory limitations in asthma patients due to respiratory obstruction. Spirometry is the gold standard for identifying obstruction diseoder in asthmatic. The high eosinophils are one marker of allergies. One of the non-pharmacological management of asthma is asthma exercise Purpose: The purpose of this study was to analyze the relationship between Forced Exhaled Volume in the first 1 second (FEV1), Forced Vital Capacity (FVC) and FEV1/FVC ratio with eosinophil levels in persistent atopic asthma Method: The design of this study was an experiment with a sample of 39 people. Measurements of FEV1, FVC and FEV1/FVC ratio measured by spirometry H-101 and eosinophils were carried out in 2 methods namely manual and automatic. The manual procedure used eosin staining and automatically used hematology analyzer. Asthma exercises are carried out 4 times a week for 8 weeks. Statistical analysis used the Spearman test Results: The relationship between FEV1 and eosinophil levels r -0,379 with a p value of 0.037; there was a correlation between FVC and eosinophils r -0.462 with a p value of 0.001; there was a relationship of FEV1/FVC -0.403 with a p value of 0.028 Conclusion: There was a relationship between improvement in pulmonary function with a decrease in eosinophil levels after following asthma exercises in persistent atopic asthma

Keywords: Keywords: FEV1, FVC, Ratio FEV1/FVC, eosinophil, Persistent atopic asthma

Topic: Sport Sciences and Physical Education

Link: https://ifory.id/abstract/pbrP8GLXhByM

Conference: The 3rd International Conference of Health Sciences (ICHS 2019)

Plain Format | Corresponding Author (Rahmaya Nova Handayani)

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