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This study aims to determine the process of theoritical service in the utilization of laboratory tools and materials and to produce an information system design that can improve the utilization service of laboratory tools and materials in Physics Laboratory of State University of Medan. This type of study is Research and Development (R & D). The procedures of this study were needs analysis, design, development and implementation. The sample which is used in this study were lectures and students of Physics Department. Product testing is devided into 4 stages : validator test, individual test, small group test, and field test. The instruments used in this study was a questionnaire in the form of responses and ratings from Physics lectures and students which is about the design of graphic and software, information system, and the service of tools and materials used. Average percentage of design testing by expert is 97,85%, information system by expert 97,7%, tools and materials management by expert 85%, individual testing 97,4%, small group testing 97,2%, and field testing 98%. The conclusion of this study is the product be in the form of Information System Application is categorized as Very Good with average percentage of all testing 95,53% and be worthy of being used as an information system for the utilization of tools and materials at the Physics laboratory of the State University of Medan.