Indonesia Conference Directory

Remek daging (Hemigraphis colorata W.Bull) have been studied and used traditionally for wound healing. This study aimed to determine the effect of topical application of 70% ethanol extract of Remek daging leaves on burn wound. The animals used for this study were 30 rats, divided into 5 groups namely 20, 10, 5% Remek daging extract ointment, negative control (Vaseline flavum) and positive control (Burnazin®). Observations were held on days 3, 7 and 14 histologically. Histological observations show an increase in the number of macrophages, fibroblasts, collagen density and re-epithelialization in the extract ointment group significantly compare to the negative control (p <0.05), and at a concentration of 20% showed comparable results to Burnazin® (p> 0.05). It can be concluded that Remek daging ointment extract can accelerate the healing of burn wound with the best results at a concentration of 20%.