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One of the health problems is infertility, with an incidence of 15-20% of around 50 million couples, which men account for about 50% of all cases. Parijoto fruit (Medinilla speciosa Blume) is empirically used to in-crease fertility. The purpose of this study was to determine the stimulatory effect of methanol extract, insolu-ble and soluble fraction of n-hexane parijoto on the quantity spermatozoa. This study used 28 male SD rats, divided into VI groups, where group I was normal; group II; III; IV; are methanol extract groups with doses 100 mg/kgBW; 250 mg/kgBW; and 500 mg/kgBW, group V is n-hexane insoluble fraction 500 mg/kgBW, and group VI is n-hexane soluble fraction 500 mg/kgBW, each given orally for 14 days. The parameter observed was the quantity spermatozoa. The data obtained were analyzed using Kruskal-Wallis, and Mann-Whitney. The results showed the mean quantity spermatozoa in groups I, II, III, IV, V, and VI were respectively 26.8±1.6; 27.1±1.3; 30.4±1.3; 43.5±1.3; 67.1±2.8; and 50.1±1.9 (million/ml ejaculate). There were significant differences between groups I and groups IV, V and VI. Methanol extract, insoluble and soluble fraction of n-hexane parijoto fruit were able to provide a stimulating effect on the quantity spermatozoa in SD male rats.