Indonesia Conference Directory

Corresponding Author
Aulia Asman

Institutions
Universitas Negeri Padang

Abstract
Physical, chemical and psychological stressors can affect GnRH pulsatile frequency and amplitude. This is important for FSH and LH secretion. Moreover, stressors can also activate the sympathetic nervous system (norepinephrine release) and adrenal medulla (epinephrine release). Catecholamines increase (epinephrine and norepinephrine) can increase GnRH pulse. The excessive pulse increase can reduce and stop FSH and LH secretion. Epinephrine is a chemical stressor, so, this research aims to prove the effects of epinephrine administration on FSH and LH level. It is an experimental laboratory research using post test only control group design. The examined variables were FSH and LH level. This study used 24 female mice (Mus musculus) consisted of 6 groups; 1 control group and 5 treatment groups based on the epinephrine administration of 0.001 mg/ml, 0.002 mg/ml, 0.003 mg/ml, 0.004 mg/ml, and 0.005 mg/ml respectively, given every day for 20 days startedfrom the beginning of proestrus cycle. Then the result was analyzed using One Way ANOVA method and followed by Multiple Comparison Bonferroni test. The result indicates that the dosagelevel in epinephrine administration indicates a significant difference (p <0.05) on FSH and LH level of 0.001 mg/ml and 0.002 mg/ml, 0.003 mg/ml, 0.004 mg/ml, 0.005 mg/ml by control. From the result, it can be concluded that chemical stressors (epinephrine) can reduce FSH and LH level. It is recommended to conduct a further research with measurement of Estrogen and Progesterone level and Catecholamine level.

Keywords
Epinefrin, FSH, LH

Topic
Medical and Surgical

Link: https://ifory.id/abstract/9pM7uVAaYUbz

Corresponding Author
Anis Ika Nur Rohmah

Institutions
University of Muhammadiyah Malang

Abstract
Introduction: The many occurrences of acute injuries due to the surgical process or accident have a considerable risk of complications if not given appropriately. Chinese Petaileaves contains saponins, tannins, and flavonoids are useful for accelerating through the process of acute wound healing. Saponins, tannins, and flavonoids had a certain function as antibacterial, antioxidant and can protect collagen which could inhibit bacterial growth, prevent infection and it also accelerates some epithelialization process effectively. Moreover, Chinese Petaileaves were easy to get and cheap. In this study, extract Chinese Petai leaf made in gel preparations to be practical, sterile, and become the latest innovation. The purpose of this study is to make the latest innovations and proved the extract gel Chinese Petai leaf effectively for the treatment of acute wounds to rats. Research Methods: Using true-experimental design with a randomized control group posttest design as an approach in this study. The experimental design was done randomly to select rats, intervention group (n = 7) and control group (n = 6) used simple random sampling. Statistical analysis of differences in the percentage of wound closure in this study used Man Whitney test. Results: The results of the statistical test analysis indicated that the first group (Extract Gel Chinese Petai Leaf) and the second group (Normal Saline) had significant differences in the percentage of wound closure on the eighth day with the score (p = 0.014) using SPSS 16.0 statistical test. Discussion: Difference in the percentage of wound closure was seen starting early in the epithelialization phase of acute wounds and more clearly on the eighth day. This is due to the contains of saponins, tannins, and flavanoids in extract gel of Chinese Petai leaf. Conclusion: Extract gel of Chinese Petai leaf effectively accelerated the closure of wound acute stage II. The gel can immediately fill the wound area so that the active components of Chinese Petai leaves is quickly absorbed by the skin.

Keywords
Chinese Petai Leaf, Acute Wounds, Rats

Topic
Medical and Surgical

Link: https://ifory.id/abstract/jQ2tgTx7wBNb

Corresponding Author
Fathiyah Safithri

Institutions
a. Medical Faculty Muhammadiyah University of Malang

Abstract
Background : Chronic renal disease is a chronic pathological process in renal that accompanied by a progressive decline in renal function and generally ends up as renal failure. Chronic inflammation and oxidative stress are key factors in progression. Black cumin extract has antioxidant and anti-inflammatory effects that is thought to repair renal tubular and inhibit progression of the damage. Objective: to evaluate the improvement of renal proximal tubules in rat with CCl4-induced chronic renal damage after black cumin extract administration. Method: Thirthy rats were divided into five groups; normal, CCl4-induced control and CCl4-induced treated with black cumin in dose 1.2 ; 2,4; 4.8 g / kgBB. Chronic renal damage induced by CCl4 i.p @ 1mL/kgBB for 8 weeks, three times in week. After CCl4 induction, administrated black cumin extract by daily intragastric gayage for 4 weeks. At the end of the study, the animal sacrificed and tissue sample were obtained. The renal was examined histologically by routine H&E staining and the amount of hyaline cast in the proximal tubule is calculated. Results and Discussions: The result showed that the amount of hyaline cast in the proximal tubule significantly decreased after black cumin extract adminstration. Conclusion: Black cumin extract decreases the amount of hyaline cast in the proximal tubule. The antioxidant and anti-inflammatory effects of Black cumin extract may modulate the improvement renal tubular.

Keywords
Black cumin; hyaline tubular cast; chronic renal damage; CCl4

Topic
Medical and Surgical

Link: https://ifory.id/abstract/ZUdVP84kC3mn

Corresponding Author
Risa Herlianita

Institutions
School of Nursing, University of Muhammadiyah Malang

Abstract
Background: Hypertension is called the silent killer because this disease is a deadly disease, this disease can give up anyone, both young and old. Risk factors for hypertension include age, gender, family history, obesity, diet, smoking habits, alcohol consumption, and physical activity. The purpose of this study was to determine risk factors related to hypertension to employees of the University of Muhammadiyah Malang. Research Method: This study used a descriptive research design using a cross sectional approach. The sample amount to 60 respondents was taken by the purposive sampling technique. Analysis using the Spearman Rank Correlation test with significance level (α) = 0.05. Result: The results of the study Showed that risk factors for hypertension include age 18-29 years (46.7 %), gender was male (56.7%), family history (51.7%), body mass index in the normal category (55%), fruit diet and vegetables 1-2 servings (88.3%, 75%), smoking in the never smoking category (58.4%), alcohol consumption in the never consuming alcohol category (93.4%), physical activity in the category of High Level (63.3%). The results of the statistical tests show that there is a relationship between risk factors of blood pressure and p value = 0.732. Conclusion: Risk factors for hypertension in Employees of the University of Muhammadiyah Malang were smoking, diet, physical activity and age.

Keywords
risk factors of hypertension, hypertension, employees

Topic
Medical and Surgical

Link: https://ifory.id/abstract/dEveWQzaukh4

Corresponding Author
Riza Fikriana

Institutions
STIKes Kepanjen Malang

Abstract
Introduction: Hypertension is a risk factor for cardiovascular disease. The blood pressure control through regular physical activities is necessary to prevent complications. Social support is one of the factors that affect the physical activities of people with hypertension. This study aims to identify the correlation between social support and physical activities of people with hypertension. Method: This study used correlational method with the cross-sectional approach. 110 people were chosen as participants using simple random sampling technique. A questionnaire asking about support from family, health workers, and peers, as well as International Physical Activity Questionnaire were used to collect the data. The statistical test conducted was Gamma Correlation Test. Results: Results show that there was no relationship between family support, health worker support, and peer support with physical activities among people with hypertension aged 45 years and above indicated by the p-value for each variable: 0.655, 0.055, and 0.857. Based on the three p-values, the support from health workers had a p-value close to 0.05. Conclusion: No correlation between social support and physical activities of the people with hypertension signifies that social support has not yet been able to be given adequately to the people with hypertension. Family, health workers, and peers are expected to strengthen their role in controlling the blood pressure of the people with hypertension through physical activities.

Keywords
Social support, physical activities, hypertension

Topic
Medical and Surgical

Link: https://ifory.id/abstract/ftXdWxGLNZYQ

Corresponding Author
Titik Agustiyaningsih

Institutions
1Lecturer of Faculty Of Health Science University of Muhammadiyah Malang
2Lecturer of Faculty Of Nursing, Airlangga University
3Lecturer of Faculty Of Nursing, Airlangga University

Abstract
Background: COPD patients will experience increased airflow resistance, air trapping, and pulmonary hyperinflation. This condition causes a decrease in FEV1 and symptoms of shortness will occur earlier. The purpose of this study was to explain the effect of autogenic training with pursed lips breathing on anxiety and FEV1 of COPD patients. Method: This research used Quasy Experiment with Pre-Post approach of control group design. The population of this research were PPOK patient in RSUD Kanjuruhan Kepanjen Malang Regency and RST dr.Soepraoen Malang. Sampling was done by Simple Random Sampling technique according to inclusion criteria with total of 40 patients. The autogenic training intervention with pursed lips breathing had done 3 times a week for 4 weeks. So the total exercise as much as 12 times. Instruments used to measure anxiety are Zung-Self Rating Anxiety Scale (SAS / SRAS) and FEV1 using spirometry. Data analysis using Paired t test, Wilcoxon and Multivariate Manova test. Result and Analysis: Multivariate test result Manova got significance value 0,021 (α 0,05). This means that autogenic training with pursed lips breathing is effective in reducing anxiety and increasing the value of FEV1 in COPD patients. Conclusion and Discussion: Autogenic training with pursed lips breathing can reduce anxiety and increase FEV1 values if done regularly and continuously. This suggests that the role of nurse as Nursing Agency in providing nursing care in patients with COPD.

Keywords
Keywords: Autogenic training, relaxation, pursed lips breathing, anxiety, FEV1, and COPD

Topic
Medical and Surgical

Link: https://ifory.id/abstract/yZuCW9kfFQhP

Corresponding Author
Zaqqi Ubaidillah

Institutions
(a) University of Muhammadiyah Malang
(b) University of Muhammadiyah Malang

Abstract
The prevalence of blood glucose control problem is higher in Indonesia. Orally administered antihyperglycemic agents (OHAs) has various side effects and it can-t control blood glucose level by single doses. Diabetes management used complementary therapies as a support the administration of OHAs can help to control blood glucose level. Caesalpinia Sappan Linn wood have substances high antioxidant and anti-hyperglycemic, that can be used to as a support therapies in stabilizing blood glucose level. This study used pretest-posttest control group design. Thirty-two subject were recruited using a purposive sampling method. T-Independent test analysis was employed (p <0,05). The result showed the provision of stew Caesalpiniasappan linn wood as a support of OHAs therapy gave a significant effect of 54.51% compared with control (p = 0,010). Caesalpiniasappan linn has a brazillin content as a transporter that helps the pancreas work in insulin secretion. Diabetics with uncontrolled blood sugar can take of drinks Caesalpinia Sappan Linn as a supporting the consumption of OHAs

Keywords
Type II Diabetes, Blood Glucose, Caesalpiniasappan linn Wood

Topic
Medical and Surgical

Link: https://ifory.id/abstract/2EPUKA8YcQnw