Indonesia Conference Directory

Corresponding Author
Siti Rofida

Institutions
University of Muhammadiyah Malang

Abstract
The microorganisms that cause infections can mutate due to excessive antibiotic exposure. One of the new drug search strategies is through exploration of active ingredients derived from plants that have been used empirically by the community. Moringa oleifera L leaf is a plant that has been used and has been shown to have antibacterial, antifungal, analgesic, and antihypertensive activities. Moringa oleifera L leaves contain secondary metabolites such as alkaloids, tannins, saponins, flavonoids, and phenols. The purpose of this study was to obtain active ingredients from the leaves of Moringa oleifera L which will be used as a Standardized Herbal Medicine product in the treatment of infectious cases. In order to get the active ingredient as an antibacterial, multilevel extraction is carried out using different polarity solvents, so that a fraction containing nonpolar, semipolar and polar compounds will be obtained. Antimicrobial potential will be tested on each fraction using the disk diffusion method. The results of identification of the compounds in the ethyl acetate fraction show the class of compounds Flavonoids, Terpenoids, Polyphenols and Anthraquinone while in the ethanol fraction Moringa oleifera L. leaves show the compounds of the compounds Alkaloids, Flavonoids, Terpenoids, Polyphenols and Anthraquinones while in the ethanol fraction Moringa oleifera L. , Polyphenols and Anthraquinone. Antimicrobial activity is shown in the ethyl acetate and ethanol fraction in both Staphylococcus aueus and Escherichia coli bacteria.

Keywords
Fractionation, Moringa oleifera leaves, secondary metabolite compounds, antibacterial

Topic
Pharmaceutical Science

Link: https://ifory.id/abstract/aufMUpe9XkCE

Corresponding Author
Riski Sulistiarini

Institutions
(a) School of Pharmacy, Bandung Institute of Technology, Jl. Ganesha 10 Bandung, Indonesia, 40132
kikyidris[at]gmail.com; riskisulistiarini[at]student.itb.ac.id
(b) Pharmacy Faculty of Mulawarman University, Jl. Gn. Kelua, Samarinda, East Borneo, Indonesia, 75243
(c) Biotech Center BPPT, Building 630 PUSPIPTEK Area, Setu, Tangerang Selatan, Banten 15314

Abstract
This study aims to determine the cytotoxic effects of Fibraurea tinctorial plants on DLD1 colon cancer cell lines in vitro and determine the IC50 values of these plants. The test begins with cell-line culture in the DMEM medium. Cultures that were ready with an estimated concentration in fresh media of 2.5x 104cells / 200uL were exposed to 0.4uL test material in 0.1% DMSO with concentrations starting at 6.25 ppm; 12.5 ppm; 25 ppm; 50 ppm; 100 ppm; 200ppm; 400ppm; 800ppm; and 1600ppm which was then incubated for 48 hours. The results are from methanol extract, hexane fraction, ethyl acetate fraction and HA and HB subfraction from Fibraurea tinctorial plants, only HB subfaction which shows inhibitory activity against DLD1 colon cancer cell line with 28% at 1600 ppm concentration

Keywords
Anticancer; dld1 Celline; Cytotoxicity Assay

Topic
Pharmaceutical Science

Link: https://ifory.id/abstract/qGF8garjmeRQ

Corresponding Author
Rohmah Susanto

Institutions
*1 Jurusan Ilmu Keperawatan, Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Malang,
*2,3 Fakultas Keperawatan Universitas Padjdjaran Bandung

Abstract
Nursing audit is an assessment of the quality of clinical nursing which is a professional evaluation of the quality of nursing services, using nursing records and carried out by the nursing profession. Based on PMK No. 49 of 2013, that the quality audit of Nursing Care and Midwifery Care is carried out by the Nursing Committee through the Professional Quality Sub Committee. This study aims to determine the effectiveness of In House Training audit of nursing care quality at RSUD Dr. Slamet Garut. The study was a cross sectional study with a descriptive design, the variables in this study were nurses knowledge of the audit of nursing care quality, a sample of 35 nurses using purposive sampling technique. The instrument used a questionnaire to determine the level of nurses knowledge about auditing the quality of nursing care. Pre-test and post-test assessments are carried out before and after the In-House-Training. Data analysis techniques used t-test to determine the effectiveness before and after the activity. The results showed an increase in nurses knowledge about nursing care audits from a mean value of 38.71 to 74.33 statistical test results obtained p=0.00 (p

Keywords
In House Training, Audit, Quality, Nursing Care

Topic
Basic Health Science

Link: https://ifory.id/abstract/dWNBz6R2fYvU

Corresponding Author
Uswatun Chasanah

Institutions
1Department of Pharmacy, Health Science Faculty, University of Muhamamdiyah Malang 65145, East Java, Indonesia
uswatun,dianerma[at]umm.ac.ud, bagasapril4,anggara.dika96, ayu7662[at]gmail.com

Abstract
Traditionally, the crushed bulbs of Dayak onion (Eleutherine palmifolia) used for wound healing due to naphthoquinone compounds found in the bulbs of Dayak onion can inhibit the growth of Staphylococcus aureus, Staphylococcus epidermis, and Pseudomonas aeruginosa that cause skin infection. To improve the ease of using the bulbs of Dayak onion as drugs for the treatment of wounds that need to be made in the appropriate dosage form is a topical hydrogel, hydrogels contained Dayak onion extract at a level of 2%, 4.5%, and 6.0% were made then determined its characterization which included organoleptic, pH, viscosity, and spreadability, determined of antibacterial activity by a well-diffusion method. The higher levels Dayak onion extract resulted in hydrogels which homogenous, sharp color intensity, more aromatic, decreased viscosity, and increased spreadability while for pH was not different, while the highest antibacterial activity achieved by Dayak onion hydrogels 6.0% which had antibacterial effectiveness to the Staphylococcus aureus, Staphylococcus epidermis, and Pseudomonas aeruginosa were 59.2%, 49.5%, and 63.1%, respectively, and as control was tetracycline HCL 1.0%. Thus, the Dayak onion hydrogels 6.0% is the best.

Keywords
Eleutherine palmifolia, Hydrogel, Antibacterial, Staphylococcus aureus, Staphylococcus epidermis, Pseudomonas aeruginosa

Topic
Pharmaceutical Science

Link: https://ifory.id/abstract/EzMQHqpduwrg

Corresponding Author
Firasti Agung N Sumadi

Institutions
a) Pharmacy Department, Universitas Muhammadiyah Malang, Indonesia
*firasti[at]umm.ac.id
b) Center for Application of Isotopes and Radiation, National Nuclear Energy Agency, Indonesia
c) Department of Medicine, Universitas Jendral Soedirman
d) Faculty of Pharmacy, Universitas Gadjah Mada
e) Department of Histology and Cell Biology, Faculty of Medicine, Universitas Gadjah Mada

Abstract
Chitosan is odorless white powder derived from the partial deacetylation of chitin which is a polysaccharide consisting of glucosamine and N-acetylglucosamine. Chitosan is commercially available in several types and has molecular weights that vary between 10,000 and 1,000,000. Chitosan has positively charged basic chain that can easily form nano complex with nucleic acid in this case including negatively charged microRNA. MicroRNA has a large role in the regulation of cancer signaling tissue so that a therapeutic approach is needed to restore balance of dysregulated miRNA. The nature of microRNA which is very susceptible to enzyme degradation requires a special system so that it is competent to deliver microRNA into the cytoplasm. One of the factors that influence the efficiency of transfection of chitosan nano complex with a nucleic acid to body cells is molecular weight. In this research,the chitosan molecular weight reduction method was carried out to increase nano complex delivery using gamma-ray irradiation. Furthermore, characterization was carried out to determine the irradiated chitosan molecular weight using intrinsic viscosity then proceed with FTIR analysis to determine changes in chemical structure and applied further by using it in nano complex formulations with microRNA 155-p, a microRNA that experienced downregulation in ovarian cancer thus requiring mimic therapy. Results showed a decrease in chitosan molecular weight after being irradiated from 110,188 dalton to 15,209 dalton while FTIR spectra showed a break of the 1-4 glycoside bonds which was equivalent to severance of the main chain of polysaccharides. Electrophoresis results showed that irradiated chitosan was able to form nanocomplex with microRNA 155-5p but transfection was not able to deliver microRNA 155-5p into the SKOV3 ovarian cancer cells.

Keywords
. irradiated chitosan; nano complex; microRNA

Topic
Pharmaceutical Science

Link: https://ifory.id/abstract/r7kRN9jGChed

Corresponding Author
Sunardi Nardi Nardi

Institutions
University of Muhammadiyah Malang

Abstract
Introduction: Blood glucose is a sugar found in the blood, formed from carbohydrates in the food and stored as glycogen in the liver and skeletal muscles. Red cooked rice is red plant rice which is cooked first. Red rice also has a fairly low carbohydrate content and also has a high fiber content. Corn rice is one of the typical dishes from Indonesia which is usually made from corn as its basic ingredient. Corn rice also has a fairly low carbohydrate content so that both rice can be food ingredients that can control the value of blood glucose. Research Methods: Using a true-experimental layout, randomization is carried out in this layout which means grouping parts of the intervention group is based on randoming. Then the pretest (O1) in both groups, and followed by intervention (X) in the treatment group. After some time posttest (O2) was carried out in both groups. The sample selection uses simple random sampling by giving red rice and corn rice for about 4 grams / day / mice to both groups. Statistical analysis of the decrease in blood glucose value in this research used the Independent T-test with a significant p <0.05. Results: The results of the statistical test analysis showed that group A which was given red rice and group B was given corn rice there was no significant difference with the significance value of the SPSS 16.0 statistical test (p = 0.978) Conclusion: There are no significant differences in group A (red rice) and group B (corn rice) findings.

Keywords
Red Rice, Corn Rice, Blood Glucose, Mice

Topic
Basic Health Science

Link: https://ifory.id/abstract/ELXpMVCFrqPW

Corresponding Author
Rollando Rollando

Institutions
aProgram of Chemistry, Faculty of Science and Technology, Universitas Ma Chung,
Malang, Indonesia
bProgram of Pharmacy, Faculty of Science and Technology, Universitas Ma Chung,
Malang, Indonesia

Abstract
Endophytic fungus was alternative source of cytotoxic metabolites derived from plant. CHCl3 fraction of ethyl acetate extract endophyte fungal genus Fusarium sp. of meniran leaves (Phyllanthus niruri Linn.) proved have cytotoxic activity in T47D breast cancer cells. This study aims to explore the active cytotoxic activity. IR, LC-MS, 1H-NMR, 13C-NMR, DEPT, and HMQC spectra showed ,3-dihydro-7-hydroxy-2-(3-hydroxyphenyl)chromen-4-one compounds. Isolate has IC50 value to T47D cells of 13.87 μg/mL and to Vero cells of 163.98 μg/mL.

Keywords
Endophytic fungus, Fusarium sp, T47D, Vero, 2,3-dihydro-7-hydroxy-2-(3-hydroxyphenyl)chromen-4-one.

Topic
Pharmaceutical Science

Link: https://ifory.id/abstract/nwErALMyZaDk

Corresponding Author
Nia Agustiningsih

Institutions
STIKes Kepanjen

Abstract
Changes in body image are normal during adolescent development but it is also a challenge for adolescents to be able to accept or adjust due to changes in body image. The existence of wrong thoughts about body image will cause a teenager to do maladaptive behavior to improve Body Image Satisfaction This study aims to determine the description of body image satisfaction in adolescents aged 16-18 years. This research is a descriptive research. The population in this study were all teenagers aged 16-18 years at SMK 5 Muhammadiyah Kepanjen with simple random sampling technique with a sample size of 176 people. The study was conducted at SMK 5 Muhammadiyah Kepanjen in April 2019. The data were presented in the form of frequency distribution tables and narratives. The results showed that respondents who have a very good body image satisfaction numbered 4 people (2.27%), either 94 people (53.41%), there were 68 people enough (38.64%), less as many as 10 people ( 5.68). Based on these results that most adolescents are able to adjust to changes in their bodies during adolescence. But there are a number of teenagers who need to be considered because body image satisfaction is in the category of insufficient and lacking so that attention needs to be given to interventions that can improve body image satisfaction.

Keywords
Body image satisafaction, adolescents, 16-18 years

Topic
Psychiatric Health

Link: https://ifory.id/abstract/D3pMGHuw9Kqt

Corresponding Author
Dyah Rahmasari

Institutions
Universitas Muhammadiyah Malang

Abstract
Background: Cymbopogon nardus is a traditional plant that has chemical content of citronella oil with potential antibacterial activity. Antibacterial peel-off mask is very easy to applicate on face. Objective: This research aim is to develop and characterize the antibacterial peel-off mask gel containing citronella oil. Method: This study used an experimental method. The peel-off mask was formulated using 8%, 10%, and 12% of polyvinyl alcohol (PVA) as a gelling agent. Evaluation of peel-off mask including physical characteristics (organoleptic, homogeneity, viscosity, spreadability, film drying time), chemical characteristic (pH value), stability and antibacterial activity. Result: The organoleptic properties showed that the citronella oil peel-off gel mask was white, aromatic and had a soft texture. The variation in PVA affects the pH value, viscosity and film drying time of the peel-off mask, significantly. Stability test showed that all peel-off mask was no significant changes physically in the freeze-thaw method, but there was some color change and phase separation in the real-time method. The peel-off mask containing citronella oil using 8% PVA has the highest inhibition against Propionibacterium acnes almost the same with the positive control (clindamycin gel). Conclusion: Variation concentration of PVA in the formula was affected on the physical and chemical characteristics and antibacterial activity of the citronella oil peel-off mask gel, significantly. The preparation using 8% PVA gives the best formula with optimal results.

Keywords
citronella oil; peel off mask gel; stability; antibacterial activity

Topic
Pharmaceutical Science

Link: https://ifory.id/abstract/j9hwGLTEzdKX

Corresponding Author
Aghnia Fuadatul Inayah

Institutions
1 Pharmacy Department, Faculty of Health Sciences, University of Muhammadiyah Malang
2 Faculty of Pharmacy, University of Airlangga
3 Dr. Iskak General Hospital Tulungagung

Abstract
Chronic Kidney Disease (CKD) can be defined as impaired kidney function that occur for > 3 months or more. This was indicated by a decrease in Glomerular Filtration Rate (GFR) (<60 ml / minute / 1.73m2). CKD stage 3 has frequent hyperphosphatemia, a complication of the disease. The effects of hyperphosphatemia are the bone minerals connection and tissue calcification process. Phosphate binder was one of therapeutic options that can be used to hyperphosphatemia. This study aims to determine the design therapy of phosphate binders used by CKD patients at hospitalization services of General Hospital Dr. Iskak Tulungagung. An observational research and retrospective. The presentation data has used descriptive of the medical record patients CKD hospitalized in the period Juli to December 2017. Phosphate binder has been used as a single therapy without combination, 130 patients (77%) used calcium carbonate, while 11 patients (7%) used calcium acetate, and of 27 patients (16%) had received switching therapy. The hyperphosphatemia therapy regimen used more calcium carbonate orally (3x500mg) in 121 patients (62%) than calcium acetate orally (1x169mg) in 16 patients (8%).

Keywords
phosphate binder; chronic kidney disease; calcium acetate, calcium carbonate

Topic
Pharmaceutical Science

Link: https://ifory.id/abstract/uhFwfbeBJGmV

Corresponding Author
nurul aini

Institutions
Nursing Studies Program, University of Muhammadiyah Malang

Abstract
Introduction : There are almost one billion young people aged between 10 and 24 years who live in Asia. These young people live in diverse socio-cultural and economic contexts, but there are important challenges and opportunities related to their sexual and reproductive health. Knowledge about reproductive health should already be possessed by adolescents, through information media it is very easy to get it. But with the vast amount of knowledge possessed by teenagers, it has not been able to foster a sense of belonging to their reproductive health status. Methods : This research was conducted with an observational research design through a cross sectional study approach. The population in this study were high school students in East Java - Indonesia. The sampling technique used was purposive sampling technique. Obtained a sample of 221 respondents. Result : The value of the results of multiple logistic regression tests conducted simultaneously on the three variables obtained significant results are as follows, X1 (0,000), X2 (0.122) and X3 (0.009). From these results it can be said that when tested simultaneously (simultaneously) X2 is said to be insignificant because of the sig value. X2> 0.005. So to determine which factors are most influential, just compare the odds ratio (OR) values of X1 and X3, which are 0.069 and 0.218. Where from the value of the two variables that have the greatest odds ratio is on biological and psychological factors. Conclusions : Various factors that become variables on adolescent awareness about reproductive health are social, economic and demographic factors, cultural and environmental factors as well as biological and psychological factors affecting the level of adolescent awareness of their health in terms of reproduction. Of the three components of the factors mentioned above, biological and psychological factors have the greatest influence.

Keywords
reproductive awareness, adolescents

Topic
Pediatric Health

Link: https://ifory.id/abstract/AnjmkW49GxCN

Corresponding Author
LaOde Saafi

Institutions
1) STIKES Mandala Waluya Kendari

Abstract
Tuberculosis can cause pain and even death, as well as can cause psychosocial and economic problems. The purpose of the study was to determine the economic losses due to tuberculosis in Kolaka Regency. This study was an analytical survey, the sample was all tuberculosis patients in 2018. The indicators used to measure the economics loss due to tuberculosis were government costs, household health costs, economic value of productive time lost due to illness and death. Analysis of government and household costs were calculated based on the cost component used for the treatment of tuberculosis, analysis of economic values due to illness using the analysis of years life with disability (YLD) and economic value dies using years of life lost (YLL) analysis. amounting to Rp.452,482,857. Household health costs amounted to Rp.28,699,500. Economic value due to illness amounting to Rp.612,068,012. while economic value died by tuberculosis in the amount of Rp.4,717,807,453. The total economic loss due to tuberculosis in Kolaka Regency during 2018 were Rp. 5,811,057,822.

Keywords
Tuberculosis, economic loss

Topic
Community Health

Link: https://ifory.id/abstract/TruELBGmh9Cx

Corresponding Author
Mulyati Mulyati

Institutions
Laboratory of Animal Physiology, Departement of tropical Biology, Faculty of Biology, Universitas Gadjah Mada, Sleman, D. I. Yogyakarta, Indonesia

Abstract
Community diet patterns that tend to be unhealthy with the consumption of fast food can cause metabolic disorders or metabolic syndromes such as diabetes mellitus. Diabetes mellitus is characterized by a chronic hyperglycemia condition that is an increase in blood glucose levels and keto-acidosis. Therapy for diabetes mellitus using synthetic chemical drugs has dangerous side effects. The otherhand there are same natural substance from plants or animals. The aims of this study examines the effect of microalgae that is suspected of being potential as an alternative medicine for the prevention or cure of diabetes mellitus. The purpose of this study was to determine the effect of administration of Arthrospira maxima and Chlorella vulgaris on the erythrocyte and platelet profiles of Wistar rats (Rattus norvegicus Berkenhout, 1769) hyperglycemia on the induction of DMT2. Twenty Wistar male rats were divided into 5 groups consisting of three control groups namely healthy controls, hyperglycemia, and drugs, and 2 treatment groups namely A. maxima and C. vulgaris. DMT2 induction uses a high carbohydrate diet and a single dose streptozotocin. Erythrocyte and platelet profiles were measured at H0, H15, and H30. Body weight and blood glucose levels are measured every 10 days. Data were analyzed using One-Way ANOVA. The erythrocyte profile was low in the control hyperglycemia rat after DM induction of H15. Erythrocyte profiles in hyperglycemia rat with this microalgae treatment, not significantly increased (p>0.05). Platelet profile in both the hyperglycemia and treatment groups was not significantly affected (p>0.05). Erythrocyte and platelet profiles in hyperglycemic rats have decreased and returned to better conditions after being given A. maxima and C. vulgaris.

Keywords
Arthrospira maxima; Chlorella vulgaris;Erithrocyte profile; Thrombocyte profile; Hyperglycemia.

Topic
Basic Health Science

Link: https://ifory.id/abstract/EVq6GFrMwAnt

Corresponding Author
Ali Multazam

Institutions
Department of Physiotherapy, Health Science Faculty, Universitas Muhammadiyah Malang
Jl. Bandung No.1, Malang City, Indonesia
*alimultazam[at]umm.ac.id

Abstract
Background: Football is a very popular sport at this time where agility, speed, and long passing are the most important components in football. Agility is a persons ability to change direction quickly and precisely without losing balance. Running speed in soccer serves to support the performance of soccer players while dribbling into the opponents area and is used to chase the ball. Agility, speed, long passing is influenced by the strength of the muscles of the lower limbs. Ankle Weight Exercise is weight training on the feet that aims to improve the strength of leg muscle strength performance. Objective: To identify the effect of ankle weight exercise to increase football player-s agility, speed, and long passing power. Research Methods: Research design is one group pre-test post-test design. The population in this study are soccer players. The total sample of 34 respondents who met the inclusion criteria. This research was conducted 3 times a week for 6 weeks. Measurements using the Illinois agility run test, 100 meters sprint test, and long pass test Results: The results of the study using the Wilcoxon test were set to 0.00 (p <0.05) for each variable. Conclusion: ankle weight exercises effective to increase football player-s agility, speed, and long passing power.

Keywords
Ankle Weight Exercise, Agility, Speed, Long Passing, Football

Topic
Community Health

Link: https://ifory.id/abstract/DwL8B3erMEnu

Corresponding Author
Aulia Asman

Institutions
Universitas Negeri Padang

Abstract
Physical, chemical and psychological stressors can affect GnRH pulsatile frequency and amplitude. This is important for FSH and LH secretion. Moreover, stressors can also activate the sympathetic nervous system (norepinephrine release) and adrenal medulla (epinephrine release). Catecholamines increase (epinephrine and norepinephrine) can increase GnRH pulse. The excessive pulse increase can reduce and stop FSH and LH secretion. Epinephrine is a chemical stressor, so, this research aims to prove the effects of epinephrine administration on FSH and LH level. It is an experimental laboratory research using post test only control group design. The examined variables were FSH and LH level. This study used 24 female mice (Mus musculus) consisted of 6 groups; 1 control group and 5 treatment groups based on the epinephrine administration of 0.001 mg/ml, 0.002 mg/ml, 0.003 mg/ml, 0.004 mg/ml, and 0.005 mg/ml respectively, given every day for 20 days startedfrom the beginning of proestrus cycle. Then the result was analyzed using One Way ANOVA method and followed by Multiple Comparison Bonferroni test. The result indicates that the dosagelevel in epinephrine administration indicates a significant difference (p <0.05) on FSH and LH level of 0.001 mg/ml and 0.002 mg/ml, 0.003 mg/ml, 0.004 mg/ml, 0.005 mg/ml by control. From the result, it can be concluded that chemical stressors (epinephrine) can reduce FSH and LH level. It is recommended to conduct a further research with measurement of Estrogen and Progesterone level and Catecholamine level.

Keywords
Epinefrin, FSH, LH

Topic
Medical and Surgical

Link: https://ifory.id/abstract/9pM7uVAaYUbz

Corresponding Author
Anis Ika Nur Rohmah

Institutions
University of Muhammadiyah Malang

Abstract
Introduction: The many occurrences of acute injuries due to the surgical process or accident have a considerable risk of complications if not given appropriately. Chinese Petaileaves contains saponins, tannins, and flavonoids are useful for accelerating through the process of acute wound healing. Saponins, tannins, and flavonoids had a certain function as antibacterial, antioxidant and can protect collagen which could inhibit bacterial growth, prevent infection and it also accelerates some epithelialization process effectively. Moreover, Chinese Petaileaves were easy to get and cheap. In this study, extract Chinese Petai leaf made in gel preparations to be practical, sterile, and become the latest innovation. The purpose of this study is to make the latest innovations and proved the extract gel Chinese Petai leaf effectively for the treatment of acute wounds to rats. Research Methods: Using true-experimental design with a randomized control group posttest design as an approach in this study. The experimental design was done randomly to select rats, intervention group (n = 7) and control group (n = 6) used simple random sampling. Statistical analysis of differences in the percentage of wound closure in this study used Man Whitney test. Results: The results of the statistical test analysis indicated that the first group (Extract Gel Chinese Petai Leaf) and the second group (Normal Saline) had significant differences in the percentage of wound closure on the eighth day with the score (p = 0.014) using SPSS 16.0 statistical test. Discussion: Difference in the percentage of wound closure was seen starting early in the epithelialization phase of acute wounds and more clearly on the eighth day. This is due to the contains of saponins, tannins, and flavanoids in extract gel of Chinese Petai leaf. Conclusion: Extract gel of Chinese Petai leaf effectively accelerated the closure of wound acute stage II. The gel can immediately fill the wound area so that the active components of Chinese Petai leaves is quickly absorbed by the skin.

Keywords
Chinese Petai Leaf, Acute Wounds, Rats

Topic
Medical and Surgical

Link: https://ifory.id/abstract/jQ2tgTx7wBNb

Corresponding Author
Gita Sekar Prihanti

Institutions
Faculty of Medicine University of Muhammadiyah Malang

Abstract
Early detection of anemia in young adolescent girls is important to optimize maternal health in the future. Prevention of anemia in junior and senior high school students is the target program of Community Health Center in Indonesia. This study aimed to determine what are the factors that affect the incidence of anemia in young adolescent girls in Junior High School 3 Kediri. An observational analytic study with cross sectional design was used to collect population data through questionnaires and blood sampling using HB Stick involved of 171 girls in Junior High School aged 10 years - 19 years. Based on the results, 78 respondents (45.6%) had anemia and 93 respondents (54.4%) did not experience anemia. From the analysis, there was a correlation of age (p 0.036; OR 0,574; CI 0.342-0,964), father education (p 0.027; OR 0.309; CI 0.109-0.877), parents income (p 0.026; OR 0.119; CI 0.018-0.776), Mentruation cycle (p 0.000; OR 0.098; CI 0.031-0.318) and Duration of Menstruation (p 0.031; OR 0.348; CI 0.129-0.904) with the incidence of anemia. There was no correlation between eating habits (p 0.999; OR 0.999; CI 0.000) with the incidence of anemia. There exist a need to giving blood tablet supplement to adolescent girls To prevent anemia in adolescent girls, it need support from family, school and community health center.

Keywords
anemia, adolescent, age, parent education, parent income, eating habits

Topic
Community Health

Link: https://ifory.id/abstract/2a8Decz9Ynuw

Corresponding Author
Timbul Supodo

Institutions
a) Mandala Waluya Institute of Health Science Kendari
Jl. Jend. AH. Nasution, Kambu, Kendari, Southeast Sulawesi
*surisaraswati[at]gmail.com
b) Mandala Waluya Institute of Health Science Kendari

Abstract
Background: Pulmonary TB prevalence is increasing every year, Andowia Health Center has the most pulmonary TB prevalence in 2015 at 57.1% who did not recover, in 2016 as many as 58.3% were not cured, in 2017 as many as 66.7% were not cured. This study aims to determine the relationship between Culture, Treatment Compliance and the Role of Health Workers with Unsuccessful Lung Tuberculosis Treatment. Method: This research is a quantitative study with a cross sectional study design. The population was 68 pulmonary TB patients and a sample of 57 people obtained by simple random sampling. Data were processed using chi-square test, closeness test and logistic regression test. Result: The results showed that out of 57 respondents, most of them were 71.9% less culture and 28.1% were good. Then 71.9% of education was low and 28.1% of education was high, 54.4% had no supervisors taking medicine and 45.6% had supervisors taking medication. Then 59.6% of family support was lacking and 40.4% were good. Furthermore, 54.4% were not compliant in treatment and 45.6% obeyed in treatment. Then 59.6% stated that the role of health workers was in the poor category and 40.4% was good. The results of chi-square test for culture p value (0.021), for education p value (0.021), for supervisors taking medicine p value (0.001), for family support p value (0.001), the role of health workers p value (0.007), treatment compliance is p value (0.004). Conclusion: There is a weak relationship between culture, education, supervisors taking medicine, family support, medication adherence and the role of health workers with the unsuccessful treatment of pulmonary tuberculosis. It is recommended for patients with pulmonary TB, so they can take medicines according to the recommended dosage. For health workers to conduct socialization and counseling about pulmonary TB disease.

Keywords
Compliance, Culture, Lack of Pulmonary Tuberculosis, Role of Health Workers

Topic
Community Health

Link: https://ifory.id/abstract/utELcCq89rM7

Corresponding Author
Dian Ermawati

Institutions
Pharmacy Study Program, Faculty of Health Sciences, Universitas Muhammadiyah Malang

Abstract
Background: Citronella oil is the most active oil against Propionibacterium acnes. An emulgel preparation is made on a carbomer base because it has better release properties of the active substance compared to other bases. Objective: to determine the emulgel variation with carbomer base 0.5%, 1.0%, and 1.5% containing 2% Citronella Oil (Cymbopogon nardus L.) on the physical, chemical characteristic and the inhibition of Propionibacterium acnes bacteria growth . Methods: Emulgel with carbomer base made 3 formulations, namely F1 (0.5%), FII (1%), and FIII (1.5%) with citronella oil content of 2%. The physical characteristics of the organoleptic, viscosity, homogeneity, dispersal, emulsion type, pH and stability (real time and freeze thaw) tests were performed. Antibacterial testing using the well method. Result: The organoleptic tests on FI (0.5%), FII (1%), and FIII (1.5%) were soft, white and has lemongrass odor. The results of one way Anova statistic showed that there were not significantly different for pH, dispersion, stability (freeze thaw and real time). The viscosity test was significantly different. The diameter of the inhibition zone of each formula has a mean of formula 1 was of 12.65 mm formula 2 was 11.58 mm and formula 3 was 10.25 mm. Conclusion: The conclusion of this experimentally is the effect of variations in emulgel on the basis of 0.5%, 1.0%, and 1.5% carbomers containing 2% Citronella Oil on the growth of Propionibacterium acnes bacteria has significant difference which means that increasing carbomer levels it can significantly reduce the zone of antibacterial inhibition.

Keywords
emulgel, citronella oil, Propionibacterium acnes, carbomer

Topic
Pharmaceutical Science

Link: https://ifory.id/abstract/MD9bnW7YdkQy

Corresponding Author
Amaliyah Dina Anggraeni

Institutions
a) Faculty of Health Science, Universitas Muhammadiyah Malang, Bendungan Sutami Street No 188A, Malang, Indonesia

*Amaliyah[at]umm.ac.id

Abstract
Pomegranate is tropical fruit contains antioxidant compounds such as ellagitannin, punicalagin, and tocopherol. Punicalagin has antioxidant EC50 54.2 ppm. This study aims to formulate and evaluate peel -off mask containing pomegranate extract. Dosage formulation of peel off mask made in various concentrations of white pomegranate peel extract that F1(1%), F2 (2%) and F3 (3%) with PVA and PEG 1500 as based. Further preparation peel off mask evaluated physical and chemical characteristics and stability during storage. The result showed that the F3 showed the highest antioxidant activity and had good physicochemical properties than the other formulas event only F1 showed good stability while storage for 28 days. The increased concentration of white pomegranate (Punica garanatum L.) extract had an effect on antioxidant activity of white pomegranate peel extract peel-off gel masks

Keywords
White Pomegranate Extract, Peel-off Gel Mask, antioxidant

Topic
Pharmaceutical Science

Link: https://ifory.id/abstract/xQ6dchVatBAR

Corresponding Author
DEWI RURY ARINDARI

Institutions
INSTITUTE OF HEALTH SCIENCE SITI KHADIJAH PALEMBANG

Abstract
Hypertension is a common non communicable disease which can lead to decrease the quality of life. The number of people with hypertension is on the increase worldwide, particularly in developing country. The World Health Organization (WHO) has identified medication adherence as the primary indication of treatments effectiveness. The number of medication adherence on people with hypertension is decreasing in the world, including Indonesia. Health Belief Model is one of the factors that influencing to medication adherence. Therefore, identifying health belief model factors relating to medication adherence among hypertensive patients is required. A cross-sectional survey design was used in this study with accidental sampling technique. Health Belief Model Factors and medication adherence questionnaires were used to collect the data. A total of 75 people with hypertension who were on medication were recruited. Descriptive statistics and Chi-square were used for data analyses. The results revealed that there were significant statistically relationships between perceived susceptibility to develop the complications of hypertension, perceived severity of hypertension complications, perceived benefits of medication adherence, perceived barriers to medication adherence and medication adherence. The patients, who have high perceptions about susceptibility to develop the hypertension complication, severity of the complications of hypertension, the benefit of medication adherence, reduce barriers to medication adherence more likely adhering to their medications.

Keywords
Health Belief Model Factors; Hypertensive Patients; Medication Adherence

Topic
Community Health

Link: https://ifory.id/abstract/dLxmeWX9MYtH

Corresponding Author
Raditya Weka Nugraheni

Institutions
1Department of Pharmaceutics, Faculty of Pharmacy, Universitas Airlangga
2Department of Pharmacy, Faculty of Health Sciences, Universitas Muhammadiyah Malang
Jl. Dharmawangsa Dalam 60286, Surabaya, Indonesia

Abstract
This study evaluated the role of HPMC to inhibit mannitol crystallization in air-dried liposome formulation. HPMC has been used in solid dispersion to prevent crystallization of several drugs. The mannitol and HPMC were included in the developed formulations with 4 different weight ratios and air-dried at 40ºC for 120 h. Liposome was composed of SPC:DDA:Chol (9:3:1 in molar ratio). XRD data showed crystalline-forming properties as function of mannitol and HPMC ratio. The formula with highest mannitol:HPMC ratio (4:1) showed most obvious crystallinity, while the lowest ratio (2:3) indicated amorphous solid. DTA analysis found that the later formula showed broad endothermic peak at 150-170ºC, indicating amorphous solid. SEM data supported these results where no crystalline structure was observed in the later formulation. The rest (2:1 and 4:3) formula showed partially amorphous and partially crystalline. From XRD and DTA data, there are two polymorphs of mannitol observed in the formulations, delta and beta-mannitol. From the findings, it can be concluded that incorporation of HPMC as dispersion matrix potentially inhibits crystal formation in the developed formulation.

Keywords
Liposome, Air-Drying, Mannitol, HPMC, Crystallizations

Topic
Pharmaceutical Science

Link: https://ifory.id/abstract/3YeGmZ4wxzAD

Corresponding Author
Aini Alifatin

Institutions
Fakultas Ilmu KesehatanUniversitas muhammadiyah malang

Abstract
Cases of violence against children in Indonesia in recent years have increased very sharply. The 2013 Survey results by KPP-PA in collaboration with Kemsos and BPS found an increase in the number of children who experienced sexual, physical or emotional violence. Data from Komnas PA in 2013 found 1620 cases of violence against children: 490 (30%) physical violence, 313 (19%) emotional violence, 817 (51%) sexual violence. The real amount can be even greater. Various backgrounds of violence are being carried out in many researches. The purpose of this study was to determine the relationship between demographic characteristics of the incidence of violence in children. The design of the study used a description of the correlation in which the study population was school-age children in grades 3, 4, 5 and 6 at Muhammadiyah Elementary School in Malang City. Simple Random Sampling obtained 347 samples. Data processing through editing, coding, scoring, and tabulating, then tested with Chi-Square. Based on the analysis of the data obtained results: based on gender, number of siblings, marital status of parents, last education of parents, and parental work, affect the occurrence of violence with a p value of 0,000 - 0,013 (ρ <0,05). So that it can be interpreted that there is a relationship between the demographic character and the incidence of violence in children. Conclusion of the study that the demographic character is the originator of violent incidents.

Keywords
demographics, relationship, child abuse, incidence

Topic
Pediatric Health

Link: https://ifory.id/abstract/4QpZMnGTAJhm

Corresponding Author
Zulfikar Muhammad

Institutions
Sekolah Tinggi Ilmu Kesehatan Kepanjen

Abstract
Background. Indonesia is a country located at the confluence of three active plates of the earth which cause earthquake pathways and active volcanoes. Sumberrejo Village is located on one of the legs of an active volcano, namely Semeru Mountain which has the potential to be affected by the volcanic eruption. The effort that can be done to reduce the impact of the disaster threat is to form the Desa Tangguh Bencana (Destana). Disaster resilient village is an activity that aims to increase the capacity of the community, namely increasing knowledge and skills in the face of the threat of disaster. The aim of the study was to find out whether disaster resilient village socialization using the SGD (Small Group Discussions) method could affect the resilience of the community in dealing with disaster risk. Method. This study uses a quantitative method with a pre-experimental design, and with a one group pretest-posttest approach. The group was pretested before the treatment, then after being treated, the group was posttest. The instrument in this study used a community resilience questionnaire with 51 question items. The number of samples in this study were 35 respondents, using cluster sampling techniques. The data obtained were analyzed using the t test with significance ρ <0.05. Results. The results of this study indicate that the average value of community resilience prior to socialization was 103.20, while the average value of community resilience after socialization was 163.23. The significance value for paired samples correlations is 0.09, which means there is no significant relationship between community resilience before and after socialization, while the paired sample test significance value is 0.00, which means that there is a significant effect between community resilience before and after socialization. Conclusion. This study can be concluded that there was an increase in the resilience of the people of Sumberrejo Poncokusumo Village after the dissemination of resilient villages using the SGD (Small Group Discussions) method.

Keywords
Disaster Disaster Village, Small Group Discussions, Community Resilience, Disasters

Topic
Community Health

Link: https://ifory.id/abstract/GRt8ukezEyDT

Corresponding Author
Diah Hermayanti

Institutions
Medical Faculty, Malang Muhammadiyah University

Abstract
Background : Iron deficiency anemia is still of the national nutritional problems in Indonesia. This anemia mainly affects women and children. In women, increased of iron need is due to pregnancy, childbirth, and breastfeeding. In infants and children this due to thier needs for growth. Iron deficiency anemia is also influenced by socioeconomic factors, malabsortion, and infection. In this study, a deficiency anemia prevention training was conducted in Busthanul Athfal teacher in Malang. Goals : comparing the average knowledge about iron deficiency anemia and its prevention before and after training. Methods : the research was conducted with training activities and pre-post test. Data was analized by comparative analytic paired Ttest. Results and discussion : The questionnaire wa filled by 46 paticipants. The avarage value of pre test wa 47.8 and the post test was 75.2. T different test 0.000 9p<0.05). There is an increase in knowledge about iron deficiency anemia and its prevention Conclusion : There was an increase in knowledge about iron deficiency anemia and its prevention after training in Busthanul Athfal teachers.

Keywords
iron deficiency anemia, knowledge, prevention

Topic
Community Health

Link: https://ifory.id/abstract/WJNVrqedbwg6

Corresponding Author
Fathiyah Safithri

Institutions
a. Medical Faculty Muhammadiyah University of Malang

Abstract
Background : Chronic renal disease is a chronic pathological process in renal that accompanied by a progressive decline in renal function and generally ends up as renal failure. Chronic inflammation and oxidative stress are key factors in progression. Black cumin extract has antioxidant and anti-inflammatory effects that is thought to repair renal tubular and inhibit progression of the damage. Objective: to evaluate the improvement of renal proximal tubules in rat with CCl4-induced chronic renal damage after black cumin extract administration. Method: Thirthy rats were divided into five groups; normal, CCl4-induced control and CCl4-induced treated with black cumin in dose 1.2 ; 2,4; 4.8 g / kgBB. Chronic renal damage induced by CCl4 i.p @ 1mL/kgBB for 8 weeks, three times in week. After CCl4 induction, administrated black cumin extract by daily intragastric gayage for 4 weeks. At the end of the study, the animal sacrificed and tissue sample were obtained. The renal was examined histologically by routine H&E staining and the amount of hyaline cast in the proximal tubule is calculated. Results and Discussions: The result showed that the amount of hyaline cast in the proximal tubule significantly decreased after black cumin extract adminstration. Conclusion: Black cumin extract decreases the amount of hyaline cast in the proximal tubule. The antioxidant and anti-inflammatory effects of Black cumin extract may modulate the improvement renal tubular.

Keywords
Black cumin; hyaline tubular cast; chronic renal damage; CCl4

Topic
Medical and Surgical

Link: https://ifory.id/abstract/ZUdVP84kC3mn

Corresponding Author
Ririn Harini

Institutions
1, Jurusan Ilmu Keperawatan, Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Malang Malang
2,Rsi Aisyiyah; Jl.Sulawesi no.16, (0341)326773

Abstract
ABSTRACT Background: during pregnancy physical and psychological changes occur gradually began to trimester 1 up to 3 trimester can cause anxiety. Anxiety in primigravida 66.2% higher compared to multigravida (42.2%). 52% of women experience increased anxiety or depression while pregnant impact of anxiety is very dangerous to pregnant women affect fetal and maternal health: pascanatal, the complications preeclampsia, premature birth, babies lose weight, APGAR score lower, emotional/behavioral issues at four years old. Based on the context, intervention of pregnancy accompanied anxiety is through the efforts of antenatal yoga. The purpose of this research is to know the Antenatal Yoga Influence Towards a decrease in the level of anxiety In Primigravida Trimester I and II in RSI Aisyiyah Malang. Methods: this study wants a method with either draft one group (One Group Pretest Posttest) with a total sample of 16 respondents. Data taken with the use of HARS questionnaire (Hamilton Anxiety Rating Scale) pre and post do antenatal yoga to get significant data with antenatal yoga. Results: based on the results of the analysis of the test of Wilcoxon by using the SPSS program, obtained a value of Z =-3.530 with tarf significancy 0.000 (p < 0.05), the value of the Sig (2-tailed) ≤ real adequate (α/2) and can be drawn conclusion H1 is accepted. Conclusion: antenatal Yoga influential in lowering the level of anxiety in primigravida trimester I and II in RSI Aisyiyah Malang.

Keywords
Yoga Antenatal anxiety level, Primigravida Trimester I and II

Topic
Maternity Health

Link: https://ifory.id/abstract/U8Rwtu2LypVJ

Corresponding Author
Hardiyanto Hardiyanto

Institutions
STIKes Kepanjen

Abstract
ABSTRACT Introduction: The incidence of cardiac arrest outside the hospital is still a frequent and even increasing frequency. While CPR volunteer assistance has been widely reported at low rates in various parts of the world (Abella, 2008). This requires the existence of other recommended methods and methods so that the level of availability and knowledge of CPR volunteers becomes greater. Teaching to early age is recommended because the earlier they know the management of CPR, the better their knowledge will be in the future. Children are learners who are quick and easy to motivate. This then encourages researchers to examine alternative methods that can be used to increase the knowledge and number of CPR Volunteers. Objective: The purpose of this study was to find out the benefits of using Puzzle games in increasing knowledge about CPR in elementary student of SD Kedungpedaringan Kepanjen. Method: Research method was Quasy experimental. The sample used was 44 people by simple random sampling. Samples were divided into 2 experimental groups, group 1 used standard teaching techniques (SAP), Group 2 used Puzzle games. Results: There was a significant effect (p <0.01) between learning using SAP / Module and Puzzle Games on the level of knowledge of respondents before and after treatment. Responded stated that he preferred learning using the Puzle game. Discussion: Puzle game is a form of educational game which functions not only as a means of play but also a form of education to students. The function of the game is to create a pleasant atmosphere for students. With a pleasant atmosphere, students can receive and understand information that is conveyed more easily.

Keywords
Educational cards game, Level of Knowledge and Fun of Learning, Learning Methode

Topic
Emergency

Link: https://ifory.id/abstract/Y4tQv6bKgwp7

Corresponding Author
Devi permata Sari

Institutions
(1,2) faculty member of Muhammadiyah Klaten health and science college
(3) student of Muhamamdiyah Klaten health and science college

Abstract
Background: Menstrual pain is lower abdominal pain originating from uterine cramps and occurs during menstruation. Menstrual pain occurs due to an increase of progesterone hormone. Menstrual pain is often experienced by teenagers and is very disturbing daily activities, thus requiring handling to reduce menstrual pain. Aromatherapy lavender is one of the treatment to reduce menstrual pain. Aims: This study aims to determine the influence of lavender aromatherapy on alleviating of menstrual pain in teenagers in Polanharjo. Methods: The method used in this research was Pre Experimental with One Group Pre-test Post-test design on the 16 female teenegers who experience menstrual pain. NRS (Numeric Rating Scale) was utilized to assess the scale of pain. Results : The results shown that the mean before lavender aromatherapy was given 3.69 and the mean after given lavender aromatherapy 2.06. Once given lavender aromatherapy there was a decrease in pain 1.63. Result of data analysis got P = 0,000, α = 0,05. Conclusion: The conclusions of this study indicate that lavender Aromatherapy affected to alleviate of menstrual pain.

Keywords
menstrual pain, lavender,

Topic
Maternity Health

Link: https://ifory.id/abstract/cLfUGqadgZFh

Corresponding Author
Nungki Marlian Yuliadarwati

Institutions
S1 Fisioterapi Fakultas Ilmu Kesehatan

Abstract
Latar Belakang : pada lansia akan mengalami penurunan pada fungsi fisiologi dan sistem tubuh. Salah satu yang menjadi permasalahan lansia adalah resiko jauh sebab dapat menganggu aktivitas sehari-hari, dari bertambahnya usia harapan hidup lansia akan meningkatkan resiko jatuh dan dapat dilihat dari prevalensi cidera pada lansia akibat jatuh tahun 2018 sangat tinggi. Tujuan : Mengetahui pengaruh latihan metode feldenkrais terhadap tingkat keseimbangan pada lansia di Dusunun Rejoso Kota Batu Metode Penelitian : Metode dalam penelitian ini menggunakan penelitian pra-experimental dengan pendekatan one group pretest-posttest design. Sampel yang diambil dalam penelitian ini yakni sebanyak 40 responden. Uji analisa data dalam penelitian ini menggunakan uji Wilcoxon dengan menggunakan program aplikasi SPSS. Hasil : Hasil analisa data menunjukkan P = 0,000 <α = 0,05 yang menandakan bahwa H1 diterima dari penelitian ini dan H0 ditolak Kesimpulan: Terdapat pengaruh latihan metode feldenkrais terhadap tingkat resiko jatuh pada lansia di Dusun Rejoso Kota Batu

Keywords
latihan metode feldenkrais, resiko jatuh,

Topic
Community Health

Link: https://ifory.id/abstract/KzGTwmLVjy2h