Page 1 (data 1 to 12 of 12) | Displayed ini 30 data/page
Corresponding Author
Ferry Achmad Firdaus Mansoer, dr., MM.,SpOG
Institutions
1) Obstetry and Gynecology Department, Faculty of Medicine, Universitas Islam Bandung
2) Faculty of Medicine, Universitas Islam Bandung
3) Medical Biology Department, Faculty of Medicine, Universitas Islam Bandung
4) Biochemistry Department, Faculty of Medicine, Universitas Islam Bandung
Abstract
Lung cancer is a cancer with the highest incidence in the world. Conventional chemotherapy for lung cancer has side effects, high resistance and toxicity, so it is necessary to search for sensitive and effective chemotherapy drugs from natural ingredients that are widely Tersedia di in Indonesia. This study aims to examine the anticancer effect of compound 1,2-epoxy-3 (3- (3,4-dimethoxyphenyl) -4H-1-benzopiran-4on) propan (EPI) which is synthesized from clove leaf oil and its combination effects with Doxorubicin on HTB183 lung cancer cells. This research is a pure in vitro experimental study of HTB183 lung cancer culture cells. Toxicity tests were carried out using the method of tetrazolium 3- (4,5-dimethylthiazol-2-il) 2,5-diphenyltetrazolium bromide (MTT) to calculate cell viability. IC50 value was obtained by analysis using probit regression calculation using SPSS software. The synergism of this compound with Doxorubicin was determined based on the value of the Combination Index (IK) using a combination test with series 1/2IC50, 3/8IC50, 1/4IC50, and 1/8IC50 and the data was analyzed using Compusyn 1.0 software. The results showed IC50 EPI compounds is 1.41(±0.86)μg/mL, and Doxorubicin is 2.21(±0.98)μg/mL. The IK value of EPI-Doxorubicin has an average value of 0.3-0.7 which means it has a synergistic effect, and the lowest value is obtained from a combination of EPI 0,63μg/mL and Doxorubicin 0,26μg/mL with CI = 0.066. In conclusion EPI compounds have anticancer effects potent to HTB183 lung cancer cells and synergistic with Doxorubicin.
Keywords
anticancer, combination, Doxorubicin, epoxy, lung cancer
Topic
Public Health and Occupational Health
Corresponding Author
Juliani Ibrahim
Institutions
Faculty of Medicine
Muhammadiyah Makassar University
Jl. Sultan Alauddin No.259 Makassar, South Sulawesi
Email: juliabox1[at]gmail.com
Abstract
Introduction Implementation of antenatal cares remains on focus antenatal care (FANC) model, however on real services WHO 2016 model also has been implemented. Aims of the study It is needed to assess the implementation of proper effect of intervention on life birth particularly to the low birth weight. Method A cross sectional study with questionnaire is used in reproductive women age in four-community health centers. All intervention on antenatal contacts was dichotomized (yes, no). Descriptive analyses were performed percentage and frequencies. Multiple logistic regressions were computed, odds ratio and (95%) confidence intervals were calculated. Results A total 227 respondent participated. Among the associated factors by bivariate and multivariate analyses showed that gestational diabetes mellitus with p value 0.011 (OR 3.97; 95% CI 0.378-11.463) preventive measure by given antibiotic asymptomatic bacteriuria with p value 0.007 (OR 0.243; 95% CI 0.086-0.685) minimum of eight contacts during pregnancy with p value 0.000 (OR 0.130; 95% CI 0.045-0.371) are strong associated with low birth weight. Conclusion Intervention with WHO 2016 model such as preventive measurement of gestational diabetes mellitus, given antibiotic asymptomatic bacteriuria and minimum of eight contacts potentially to low birth weight outcome.
Keywords
Antenatal care; model; measurement; low birth weight
Topic
Public Health and Occupational Health
Corresponding Author
Sugiatmi Sugiatmi
Institutions
1 Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta
sugiatmi[at]umj.ac.id
2 Faculty of Public Health, Universitas Muhammadiyah Jakarta
Abstract
Background Prevalence of hypertension in adolescents increases. There are only few studies of hypertension prevalence and its association with fast food consumption and physical activity in Indonesian adolescent. Objective This study determine the blood pressure status and its association with fast food consumption and physical activity in adolescent Method. This cross sectional study was conducted during January and August 2018 in Senior High School in South Tangerang, Indonesia. 220 students were selected by proportional stratified random sampling. Blood pressure measurements were categorized as normal, prehypertension, or hypertension using the 2004 Fourth Report blood pressure screening recommendations. Fast food consumption was collected using Food Frequency Questionnaire and divided into often and rare. Physical activity was categorized using Baecke questionnaire into active and not active. Associations between fast food consumption and physical activity with blood pressure were determined using Chi Square test. Results Prevalence of prehypertension was 11.5% and hypertension was 12.0%. Fast food consumption and physical activity were not associated with prehypertension/hypertension (p value > 0.05). Conclusion Hypertension and prehypertension were highly prevalent in the studied adolescent. There were no associations between fast food consumption and physical activities with adolescent blood pressure.
Keywords
Fast food, physical activity, hypertension, adolescent
Topic
Public Health and Occupational Health
Corresponding Author
Roselina Panghiyangani
Institutions
(1)Faculty of Medicine, (2)Master Program in Public Health, (3}Bachelor Program in Public Health, Faculty of Medicine, University of Lambung Mangkurat.
Corresponding author :
roselina.darma[at]gmail.com
Abstract
Fluor albus is a symptom very often experienced by most women. Fluor albus is classifie into two types, namely, physiological and pathological fluor albus. The pathological fluor albus is caused by infection or inflammation which can lead to many problems in the reproductive health of teenagers. The purpose of this study was to analyze the effectiveness of health education on the knowledge, attitude and motivation about vaginal hygiene and prevention of fluor albus in An-Najah Aliyah School female students. Research design was pre-experimental pretest and posttest one group design. The population of this study were 130 female students of An-Najah Aliyah School, from which a sample size of 64 female students were selected. Sampling was conducted with proportional stratified random sampling technique. The research data were analyzed with the Wilcoxon test. The results showed that there were significant differences in the knowledge, attitude and motivation of the female students between before and after being given health education about vaginal hygiene and prevention of fluor albus (p value < 0.05). The conclusion is that health education is effective in increasing the knowledge, attitude and motivation about vaginal hygiene and preventing fluor albus of female students in Aliyah An-Najah School.
Keywords
fluor albus, reproductive health, knowledge, attitude, motivation
Topic
Public Health and Occupational Health
Corresponding Author
ARIF WIDODO WIDODO
Institutions
Nursing Study Program – Health Science Faculty – Muhammadiyah University of Surakarta, Indonesia
Abstract
Foreword, Minimum service standards (MSS) in the health sector are a reference for district / city governments in providing health services entitled to be obtained at a minimum level by every citizen. Every person with a mental disorder (PwMD) has the right to get the minimum service according to the standard provided by doctors and nurses in the civil health center working area. The results of this study are; 1) the good commitment revealed by the head of the District Health Office by implementing some good policies in order to improve community mental health, but unfortunately they are still at limited common policies. 2) Minimum mental health service standards have not yet been carried out, 3) The implementation of health promotion involved families and the community. Conclusion: MSS mental health has not been done in accordance with the community expectations. The community expects that mental health services can be carried out at the nearest Civil Health Center. Suggestion: MSS mental health needs to bemore optimized by involving nurses, other health workers and the community.
Keywords
Minimum service standards, Mental health services, shackled
Topic
Public Health and Occupational Health
Corresponding Author
Nofal Agnia Dendy
Institutions
1Faculty of Medicine Universitas Islam Bandung
2Clinical Pathology Department, Universitas Islam Bandung
3Public Health Department, Universitas Islam Bandung
Abstract
Scabies is the most common skin disease, which mostly occurs in developing countries. In Indonesia, out of 12 most common skin diseases in Indonesia, scabies is ranked third. Identical scabies disease with diseases that occur in santri in Islamic Boarding Schools, with the incidence of scabies in Islamic Boarding Schools that vary between 13.48% -89.9% and 4.6−12.95%. The level of knowledge and awareness to behave in a clean and healthy life (PHBS) is one of the factors that cause scabies. Based on that this study aims to make a practical module in the form of a "Healthy Santri Pocket Book" containing material about personal hy-giene and scabies to reduce the incidence of scabies in Manarul Huda Islamic Boarding School Bandung as an innovation free scabies boarding school which is expected to become a role model " West Java Islamic Boarding School Healthy, Free of Scabies ". This study is an observational analytic study with a cross-sectional approach. This study aims to assess the knowledge and its effect on the incidence of scabies in santri before and after being given a "Healthy Santri Pocket Book". Pre-test and post-test contain questions about personal hygiene (PHBS) and scabies that are in accordance with the material contained in a healthy santri pocket book. Santri respondents in Manarul Huda Islamic Boarding School in Bandung who were af-fected by scabies before being given the "Healthy Santri Pocket Book" were 27 respondents (81.8%) and af-ter being given "Healthy Santri Pocket Book" there was a decrease in the incidence of scabies to 15 respond-ents (45.4%). In the research results found the pre-test results were 86.67. There was an increase after being given a healthy santri pocket book to 94.8. Based on the results of statistical analysis it can be seen that p <0.05 (P = 0.008) which means that there is an influence on the provision of PHBS material by giving a healthy santri pocket book statistically.
Keywords
Islamic Boarding School, Pocket Book, Scabies.
Topic
Public Health and Occupational Health
Corresponding Author
yuli susanti
Institutions
1) Public Health Department, Medical Faculty Universitas Islam Bandung, Bandung, Indonesia
*yulisusantiarmandha[at]gmail.com
2) Medical Faculty Universitas Islam Bandung, Bandung, Indonesia
3) Orthopaedic and traumatology Department, Cibabat Hospital, Bandung, Indonesia
Abstract
Background: Work-Related Musculoskeletal Disorder (WRMSDs) are frequent health problem in industrial sector. WRMSDs are associated with work pattern like body position, repetitive movement, and duration of work. This study aims to analyze employment periods and working posture that affect to musculoskeletal disorder in bag fertilizer tailors. Methods: This research is a cross-sectional study carried by observational method. We observe 50 tailors of PT Pupuk Kujang with consecutive random sampling. Data regarding working posture collected using Rapid Upper Limb Assessment (RULA), and musculoskeletal problem assessed with Nordic Body Map (NBM). We analyzed the data using SPSS with chi-square test. Result and discussion: as many as 40% of respondent have employment periods more than 10 years, and 88% of respondent have risk category in working posture. As many as 72% of respondent have musculoskeletal complaints, there are 64% of respondent complain in upper musculoskeletal and 48% have lower musculoskeletal complaint. Based on chi-square test there are no relation between the employment period to musculoskeletal disorder, so as the working posture to musculoskeletal disorder. Conclusion: despite of high percentage of risk category in working posture, there is no correlation to musculoskeletal complaint due to body adaptation to daily working process.
Keywords
posture; nordic body map; musculoskeletal disorder
Topic
Public Health and Occupational Health
Corresponding Author
Titik Respati
Institutions
Faculty of Medicine, Universitas Islam Bandung , Bandung, Indonesia
Kummara Game Studio, Bandung, Indonesia
Abstract
Mental health problems in Indonesia are very important public health problems. Stigma on people with mental health disorders is one of the inhibiting factors that needs to be minimized. Adolescents are a group that needs to get this knowledge but become a group that has not received special treatment. The study aims to develop interactive approach (gamification) to support the socialization process and increase understanding on mental health. This is a pre-posttest study design using Carpe Diem Board Game. A total of 24 participants recruited through a purposive sampling and participated in the board game trial. Pre and post-test using the Depression Literacy focuses on two aspects: personal views related to depression and stigma as well as personal beliefs about the views of the surrounding environment related to depression and sigma. The results showed the learning process based on the game gives significant results at each point (pre and posttest changes). When the results of the post-test give little value is an indication that the learning process based on carpe diem that has been done is able to provide understanding and minimize the stigma associated with depression. It is concluded that indicate that game-based learning has an effect although some area still need improvement.
Keywords
Mental health, Adolescent, Carpe Diem Board Game, Indonesia
Topic
Public Health and Occupational Health
Corresponding Author
Eka Nurhayati
Institutions
1Department of Public Health, Faculty of Medicine, Bandung Islamic University
2Kummara, Bandung
Abstract
This paper presents a design and preliminary results of our initiatives to explore gamification approach to in-crease mental health awareness for Indonesian youth. Consider the current knowledge about mental health among youth in Indonesia, mixed method using both qualitative and quantitative approach was proposed as this research method. These approach is believed to be best to understand stigma on people with mental health disorder among youth.
Keywords
gamification approach, mental health awareness, disorder among youth
Topic
Public Health and Occupational Health
Corresponding Author
Nurul Romadhona
Institutions
a) and c) Public Health Department, Faculty of Medicine, Bandung Islamic University
b) Clinical Pathology Department, Faculty of Medicine, Bandung Islamic University
d) Histology Department, Faculty of Medicine, Bandung Islamic University Tamansari 22, Bandung, Indonesia, wida7089[at]gmail.com
Abstract
Various efforts have been made by the government to reduce the incidence of tuberculosis (TB) which is still high in Indonesia, ranging from prevention and treatment, but still has not reached the target. Good knowledge and affective of TB patients are expected to reduce TB transmission. The purpose of this study was to analyze the correlation between knowledge and patient attitudes regarding TB. This research method is the Spearman correlation test, with 60 respondents of tuberculosis patients coming to the clinic at one of the hospitals in Bandung Regency, Indonesia. The study was conducted in March 2018. The results of this study found the characteristics of the respondents most women, the most age in the range 18-35 years, the level of higher education, and many who work. Correlation test obtained r value of 0.771, with p 0.014 which means that there is a strong significant correlation with a positive direction. Conclusion The higher the patients knowledge, the better the patients attitude regarding tuberculosis. Attitude is one of the factors that determine a persons behavior. In determining attitudes, knowledge of a particular subject / object is needed. A persons knowledge can be influenced by several factors, including the level of education.
Keywords
attitude, knowledge, tuberculosis
Topic
Public Health and Occupational Health
Corresponding Author
Eka Nurhayati
Institutions
Medical Faculty of Unisba
Abstract
Depression is one of mental disorders that can affect teenagers. Negative stigma against depression may cause patients not to have appropriate professional treatment, thus the patient might get worse even can ended up with suicide. Psycoeducation is one of many ways that used by professional health care to reduce stigma against depression especially among teenagers. This study was accomplished to measure the effectivity of psycoeducation by comparing the level of stigma against depression pre and post psychoeducation among teenagers. This was an analytic, cross sectional research. Study focused on 37 teenagers who was given psychoeducation by psychology professional. The tool that was used to measure stigma was Depression Stigma Scale (DSS). It has two 9-items sub scale assumed to measure personal stigma and perceived stigma. The DSS was given before and after the psychoeducation. Results obtained from unpaired t test showed two tailed p value 0,90 (95% CI -1.63 to 1.43) for personal stigma and 0,35 (95% CI -1.09 to 3.05) for perceived stigma. Conclusion of this research was that psychoeducation cannot reduce the level of stigma against depression among teenagers.
Keywords
Psychoeducation, stigma, depression, teenagers
Topic
Public Health and Occupational Health
Corresponding Author
Yudi Feriandi
Institutions
a) Department of Occupational Medicine, Faculty of Medicine, Universitas Islam Bandung
Jalan Tamansari 22 Bandung 40116, Indonesia
*yudiferiandi3[at]gmail.com
b) Department of Public Health, Faculty of Medicine, Universitas Islam Bandung
Jalan Tamansari 22 Bandung 40116, Indonesia
Abstract
The main production problem of the small industries is Manual Material Handling (MMH) that will raise risks of musculoskeletal injuries. This research was conducted to assess the risk of musculoskeletal injury among Small scale industry using the Ovako Working Posture Assessment System (OWAS) approach as a method of identifying the potential of musculoskeletal injuries. This is a case study of twelve workers from nine small industries in Bandung Indonesia. Ergofellow 3.0 software was used to measure OWAS scores. The results of the study showed that six of the workers were in category two, and the rest were in category three. Data showed that eight from twelve workers have score four, which is high risk on their back posture. These findings confirmed the high risk of musculoskeletal injury, especially diseases involving the back region. Stakeholder of the occupational health needs to take corrective action to minimize the risk of musculoskeletal injury.
Keywords
musculoskeletal; OWAS; occupational Health; industry
Topic
Public Health and Occupational Health
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