Indonesia Conference Directory

Corresponding Author
Agnes Wina Goran

Institutions
1 Departemen Sistem Informasi, Universitas Komputer Indonesia, Indonesia
2 Departemen Teknik Informatika, Universitas Komputer Indonesia, Indonesia

Abstract
The purpose of this research was to provide information about the prediction of student interest in the laptop specifications through the application of data mining using the c4.5 algorithm. The method used in this research is a survey method by conducting interview. This research was conducted by conducting interviews with several students. The results of this research was a decision tree that describes the laptop specifications that is most in demand by students, so students who want to have a laptop can easily determine laptop specifications based on the number of enthusiasts on certain laptop specifications. The technique used in the application of data mining in this research is a classification technique. The conclusion in this research is that by implementing data mining, students didn-t need to look for various sources to find laptop specifications that are needed by students in meeting their college needs in long time.

Keywords
E-Commerce

Topic
Electrical and Computer Engineering

Link: https://ifory.id/abstract/VrGxPdjKy3XC

Corresponding Author
M. Wildan Julian P.

Institutions
a. Departemen Teknik dan Ilmu Komputer, Universitas Komputer Indonesia, Indonesia
*ranggaprtm95[at]mahasiswa.unikom.ac.id

b.Departemen Ilmu Pemerintahan, Universitas Komputer Indonesia, Indonesia

Abstract
The internet is the most important thing that is always used today. Among the many uses and uses in the business world. The purpose of this study is to find out how much influence the internet has on the business world. With the world of internet business is growing rapidly and increasingly sophisticated. The method used in this article is the literature study method. The results of this article are the importance of the internet in the business world, where businesses will grow rapidly as the technology grows faster. In this case also supporters of the business world, namely the internet is supported by the development of technology that makes it easier to do business in terms of documentation and transactions. Anywhere and even anyone can do business if using the internet. Especially the internet can be used as a media campaign, ease of transaction, and others. With the internet profitable for entrepreneurs because it can increase business connections and expand the global network and spread to all circles.

Keywords
internet, Business

Topic
Entrepreneurship & Technopreneurs

Link: https://ifory.id/abstract/buGNaCM2Efrc

Corresponding Author
Muhamad Nursalman

Institutions
Universitas Pendidikan Indonesia

Abstract
In the field of communication there are services that function as a means of community service. This service is useful for facilitating or accelerating community action in reporting and providing first aid to the authorities. The form of assistance services is oriented towards public complaints on emergency services. However, in this study it will only be more emphasized for complaints services related to the Polsek agency. In addition to the positive aspects of this service, there are also negative impacts such as sending fake data or misuse of someones data, therefore a Complaint Service security system is created using the Two Central Facilities Protocol, assisted by cryptographic security methods using the RC6 algorithm, which when when the login reporter will enter the validation number generated with One Time Password sent via email which aims to find out that the reporter is actually logged in and for the reporter report data security using the RC6 algorithm which is used when encryption and decryption of reporting data is sent to the police station or police station. From the system, obtaining the assessment of the user or user, the following are aspects of the assessment: Usability, Information Quality, and Interaction Quality from all aspects get an average value of 81%, 82.8%, and 83.1%.

Keywords
Complaint Service, RC6 Algorithm, One Time Password, Protocol Two Central Facilities, Cryptography

Topic
Computer Science

Link: https://ifory.id/abstract/dcTyuRp8JFD6

Corresponding Author
Yaya Wihardi

Institutions
Universitas Pendidikan Indonesia

Abstract
In this research, we present a low cost motion capture system for 3D character animation by utilizing RGB-D sensor such as Kinect. The system capture the human motion and apply it on a 3D character. Animated 3D character recorded by a 3D animator environment and rendered as a part of animation production. In order to evaluate time execution of the system, we compare two rotation methods: Euler and Quaternion. The result show that Quaternion more efficient than Euler.

Keywords
motion capture, animation, Kinect

Topic
Computer Science

Link: https://ifory.id/abstract/rNW97Ptw2gKd

Corresponding Author
Samsul Hidayat

Institutions
1) Jurusan Fisika FMIPA Universitas Negeri Malang
2) Jurusan Biologi FMIPA Universitas Negeri Malang
3) Jurusan Kimia FMIPA Universitas Negeri Malang
4) Jurusan Elektro FT Universitas Negeri Malang
5) Mahasiswa Jurusan Fisika FMIPA Universitas Negeri Malang

Abstract
The Unmanned Aerial Vehicles (UAV) technologies are growing rapidly. This is supported by sensor, control, and actuator technology. The development of UAV technology strongly supports for surveys, exploration, real-time monitoring territory, and so on. Multirotor UAVs is use brushless motors as a driver for moving. Brushless motor controlled by ESC. ESC receives DC power to be converted into commutative DC to drive brushless motors. ESC actually also senses the position of brushless motor rotors in determining their command. Battery energy efficiency, critical, the remaining flight time are important thing of UAVs. For this reason, the purpose of this research is to create a device that can be used for consumption monitoring of wireless brushless motor with Android smart phone devices. The steps taken are the design of android smart phone software / applications and design of current sensors with the hall effect phenomenon. The large magnetic field in the current of the wire is directly proportional to the large current through the conductor, and inversely proportional to the square of the distance. The magnetic field can cause concentrations of electrons to certain sides of each conductor plate. This phenomenon can cause a potential difference in the conductor plate and is often called the hall effect. Magnitic flux is continued by the permeability of the material exposed to magnetic flux. By providing iron core material, or ferrite ring, magnetic flux will accumulate on the ferrite ring. The hall sensor inserted at the space of the ferrite ring will be more rich in magnetic flux. This is used for measuring current without breaking the conductor. The hall of the voltage value are transmitted with the HC-05 bluetooth module to the Android smart phone for displaying..

Keywords
wireless, current sensor, bluetooth

Topic
Electromagnetic Methods

Link: https://ifory.id/abstract/HkgFyXeb2Mw6

Corresponding Author
Randa Dwi Saputra

Institutions
Economics and Business Faculty, Mulawarman University Jalan Tanah Grogot 1, Samarinda 75119, Indonesia.
*randa.saputra12[at]mhs.feb.unmul.ac.id

Abstract
This study aims to analyze the effect of Working Capital as measured by working capital turnover and Leverage as measured by the debt to equity ratio to the profitability of the company. Company profitability is measured by the return on equity ratio. The research sample is coal mining companies listed on the Indonesia Stock Exchange in 2014, 2015 and 2016. The data collection method used in this study is library research which is useful to obtain an overview or condition or theoretical foundation related to the research title. The statistical method used is multiple linear regression. The results showed that (1) Working Capital has a positive and not significant effect on company profitability; and (2) Leverage has a negative and significant effect on company profitability.

Keywords
Working Capital; Leverage; Profitability

Topic
Manajemen Keuangan

Link: https://ifory.id/abstract/BKxNcCMFw3JD

Corresponding Author
Mutmainah Arif

Institutions
1Graduated School, Hasanuddin University, Indonesia
2Departement of Biochemistry Faculty of Medicine, Hasanuddin University, Indonesia
*ikayustisia[at]gmail.com

Abstract
Objective: This study aims to see the development of tumor tissue in rats given the combination of ethanol extract of Moringa leaves (Moringa oleifera L.) and ethanol extract of papaya leaves (Carica papaya L.) as an alternative to increasing nutrition in slowing tumor tissue which will be used for further studies on phytotherapy as an alternative medicine for cancer. Methods: This study was conducted experimentally using a laboratory Complete Random Design (CRD) method. Results: The results show that there are different changes in body weight between groups for 12 weeks. However, based on the results of the one way ANOVA test, there is no significant differences between groups (p> 0.05). The appearance of tumor tissue was detected at week 7 in the comparison group (DMBA). Whereas in the positive control group and the combination extract group, the solid period began to be felt at the 10th week. Based on the results of histopathological tests in rat organs show that the growth of cancer tissue in all test animals in the treatment group given by DMBA. Conclusion: The combination from ethanol extract of Moringa leaves (Moringa oleifera L.) and ethanol extract of papaya leaves (Carica papaya L.) at a dose of 150 mg/kgBB has activity in slowing the formation of cancer tissue.

Keywords
Moringa leaves; papaya leaves; breast cancer; DMBA.

Topic
Herbal medicine

Link: https://ifory.id/abstract/kvZyn9MbXKrQ

Corresponding Author
Retno Ambarwati Sigit Lestari

Institutions
Chemical Engineering Department, University of 17 Agustus 1945 Semarang, Indonesia

Abstract
This study tried to explore characterization of biodegradable plastic from jackfruit seeds and rice waste. Jackfruit seeds and rice waste contain starch, so it can be used for plastic material with addition of several additives such as polyvinyl alcohol (PVA), glycerol, chitosan and sorbitol. Starch is one of polysaccharides that be used as raw material for biofilms. Polyvinyl alcohol is the most important plastic in making water-soluble films. It was ability to form films, emulsifiers, and its adhesive properties. Polyvinyl alcohol has high tensile strength, good flexibility, and good oxygen barrier. Sorbitol and glycerol are also an additive in the manufacture of biodegradable plastics from starch, which is a plasticizer that increase elasticity. Chitosan have effects to bioplastic, such as biodegradable, hydrophilicity, and anti bacterial. This research aims to determine the effect of addition of PVA, glycerol, chitosan and sorbitol to optimum characteristics of bioplastic. The parameters to be examined bioplastic include thickness, moisture content, tensile strength, and % elongation. Increasing of glycerol added to the plastic material effect to decrease of tensile strength of bioplastic and elongation, lower water resistance and more easily degraded. Increasing of chitosan added to the plastic material effect to higher tensile strength, lower elongation, higher resistance to water and lower degradation. Increasing of PVA added to the plastic material effect to increasing of the tensile strength of the bioplastic and decreasing of elongation of bioplastic, but the increasing of sorbitol effect to decreasing of tensile strength and increasing of elongation of bioplastic.

Keywords
biodegradable plastic, elongation, jackfruit, starch, tensile strength, waste of rice.

Topic
Polymer

Link: https://ifory.id/abstract/WmYnJgPNt3F8

Corresponding Author
Ferdy Semuel Rondonuwu

Institutions
Department of Physics, Faculty of Science and Mathematics, Universitas Kristen Satya Wacana, Jl. Diponegoro 52-60, Salatiga, Indonesia

Abstract
Introduction The study focuses on the light-harvesting function of carotenoids. How carotenoids capture the photon energy and efficiently transfer its singlet energy to the neighboring bacteriochlorophyll in the pigment-protein antenna complexes (LH2) has been studied. The 11Bu- state in the light-harvesting function are critically investigated, tracing the excited-state dynamics of carotenoids free in solution and bound to the LH2. Aim of the study The goal of this study is to reveal the detailed mechanisms of light-harvesting function. The research focuses on the roles of the 11Bu- state in the light-harvesting function of Cars. A series of investigations were carried out to critically examine the roles of the 11Bu- state in the light-harvesting function. Method The internal conversion processes in Cars were investigated by the use of subpicosecond time-resolved absorption spectroscopy for a series of Cars in solution and bound to the pigment-protein antenna complexes. including neurosporene (n = 9), spheroidene (n = 10), lycopene (n = 11), anhydrorhodovibrin (n = 12) and spirilloxanthin (n = 13). The SVD and global fitting were applied to of spectral-data matrices. Results The results lead to a branched relaxation scheme of energy deactivation including (1) the singlet internal conversion in the sequence of 11Bu- 11Bu- > 21Ag- > 11Ag- (ground), and (2) the singlet-to-triplet conversion of 11Bu- > 13Ag followed by triplet internal conversion of 13Ag > 13Bu. The relaxation scheme took place in subpicosecond to decapicosecond time scales. Conclusion The 11Bu- state plays essential roles in light-harvesting mechanisms as a mediator state in the process of internal conversion, an acceptor state in the Car-to-BChl singlet-energy transfer and a precursor state for the rapid formation of the Car triplet state.

Keywords
Carotenoid singlet energy, relaxation scheme, SVD, Light-harvesting

Topic
Biology

Link: https://ifory.id/abstract/HRLQzm7qNCtg

Corresponding Author
Ainun Ayu Lestari

Institutions
Universitas Hasanuddin

Abstract
Climate is defined as the average size and variability of the relevant quantities of certain variables over a period of time with a period of time from monthly to annual or millions of years. This study aims to develop climate prediction models that are used for planning agricultural cultivation activities. The method used in predicting climate is Backpropagation Artificial Neural Network technique based on rainfall data in 1975-2018 in Pallangga sub-district, 1992-2018 in Bontomarannu sub-district and 1997-2018 in Bontonompo sub-district. The results showed that the climate classification according to Oldeman in Bontomarannu sub-district was in the B3 climate type suitable for planting rice crops twice and crops once a year while Pallangga sub-districts and Bontonompo sub-districts were in C3 climate type suitable for planting one-time rice crops and crops twice in one year.

Keywords
Climate, Artificial Neural Network, Backpropagation, Cropping Pattern

Topic
Climate Change

Link: https://ifory.id/abstract/ftG4w6Tvbq3p

Corresponding Author
Mayvita Muntadiroh

Institutions
Faculty of Medicine University of Islam Malang
Address: Jl. MT. Haryono 193 Malang, East Java province, Indonesia 65145
*Correspondence: Dr. dr. Doti Wahyuningsih, M. Kes
E mail address: dotiwahyuningsih[at]unisma.ac.id

Abstract
Introduction: Osteoarthritis (OA) is a chronic degenerative disease associated with inflammatory process and free radical formation. It causes progressive joint cartilage damage. The rhizome of red ginger and cogon grass (RGCG) have anti-inflammatory and antioxidant properties. This present study aimed to evaluate the effects of RGCG treatment on nitrate level of plasmatic and synovial membrane tissue of Wistar rats. Materials and methods: Twenty five male Wistar rats were grouped into five; control (CTL), osteoarthritic rats (OA), and 3 different doses of treatment groups (P1, P2, P3). Each rat of OA and treatment groups were given 0,1 ml right knee intraarticular complete Freund-s adjuvant (CFA) injection to induce local osteoarthritic state. All treatment groups were orally administered with 40 mg/day of I. cylindrica decoction. However, P1, P2 and P3 groups were given 9, 18 and 36 mg of Z. officinale decoction each day for 10 days, respectively. Nitrate level was measured with nitric oxide colorimetric assay kit. Plasmatic nitrate data was analyzed by Kruskal-Wallis and continued with Mann-Whitney. However, nitrate level of synovial membrane tissue was using oneway ANOVA continued with Post Hoc. Result were considered to be significant at P<0,05. Results: Plasmatic nitrate level of treatment groups was 4.3 ± 0.55, 3.91 ± 2.39, and 3.64 ± 0.7 nmol/µL respectively in P1, P2, and P3. These were significantly lower than OA group (7.15 ± 2.68 nmol/µL, P<0,05). In addition, synovial membrane tissue nitrate level of treatment groups was 2.99 ± 1.18, 2.79 ± 1.09 and 2.87 ± 0.41 nmol/µL respectively in P1, P2, and P3. These were significantly lower than OA group (3.84 ± 1.56 nmol/µL, P<0,05). Conclusions: The administration of RGCG decoction reduced the level of nitrate both in blood plasma and synovial membrane tissue in osteoarthritic-induced Wistar rats. The combination of Zingiber officinale and Imperata cylindrica may have potential as an anti-osteoarthritis agent.

Keywords
osteoarthritis, Zingiber officinale, Imperata cylindrica, nitric oxide

Topic
Biomedical Science

Link: https://ifory.id/abstract/7ADzTwvKdmgP

Corresponding Author
Wahyu Andy Nugraha

Institutions
Department of Marine Science, Universitas Trunojoyo Madura, Bangkalan, Indonesia 69162
E-mail: wahyuandy[at]trunojoyo.ac.id

Abstract
Coral recruitment is a very important component in the management of coral reefs. Coral recruitment is the main factor in the recovery of the coral community. The high recruitment of corals is an indication of natural recovery in the reef community. This study aims to determine the density of coral recruitment in Gili Pandan Island at a depth of 3 meters and 8 meters. Two sites were used as sampling station. Juvenile corals with diameters less than 5 cm were observed in quadratic transects with 1x1 meter sizes randomly and performed with 10 repetitions at each point. Coral density was calculated for the determination of recruitment rates. T-test was used to determine whether there is a difference in coral recruitment between 3 and 8 meters depth. The results showed that the average density of coral recruitment of site 1 and site 2 at depth of 3 meters were 5,9-7,6 ind/m2, categorized as high recruitment, while at a depth of 8 meters were 3.3-4.3 ind/m2, categorized as low recruitment. T-test result showed that there is significant difference of coral recruitment density between 3 and 8 meter depth both at site 1 and 2.

Keywords
Recruitment; Coral; Density; Gili Pandan Island

Topic
Bioconservation

Link: https://ifory.id/abstract/wXYHaRgV6Gr7

Corresponding Author
- Insafitri

Institutions
Department of Marine Science, Universitas Trunojoyo Madura, Bangkalan, Indonesia 69162
E-mail: insafitri[at]trunojoyo.ac.id

Abstract
Gili Labak has a good coral reef condition, but has a lot of problem including coral disease. This study aims to identify bacteria that are associated with Acropora formosa corals which have the potential as antibacterial white plague disease in Acropora sp. The method used in the antibacterial test is the overlay test and agar diffusion test, and laboratory analysis using bacterial isolation, DNA extraction, DNA amplification, squencing and phylogenetic analysis. Based on bacteria morphology, four bacterial isolates were found from healthy Acropora, namely AF1, AF2, AF3, and AF4. From the results of the antibacterial activity test using the pathogenic bacterium Bacillus firmus, isolates AF1 produced a inhibition zone in three days of 5.10 ± 0.10 mm, 2.7 ± 0.04 mm, and 3.80 ± 0.02 mm, respectively, while AF3 produced a inhibition zone of 2.90 ± 0.16 mm, 3.10 ± 0.06 mm, and 2.7 ± 0.11 mm, respectively. Meanwhile, the antibacterial activity test using pathogenic bacteria Bacillus dretensis, AF2 produced a inhibition zone of 3.80 ± 0.01 mm, 2.20 ± 0.15 mm, and 1.30 ± 0.09 mm, respectively, while AF4 produced a inhibition zone of 4.60 ± 0.060 mm, 2.90 ± 0.06 mm, and 1,00 ± 0.06 mm, respectively. The phylogenetic analysis showed that AF1, AF3 and AF4 had 99% similarity with Virgibacillus salarius, and AF2 had 98% similarity with Halomonas sp.

Keywords
coral disease; white plague; acropora formosa; antibacterial

Topic
Bioconservation

Link: https://ifory.id/abstract/xXBbfmM6LzRd

Corresponding Author
Vera Budi Lestari Sihotang

Institutions
Herbarium Bogoriense Research Center for Biology Indonesian Institute of Sciences

Abstract
This study reveals medicinal plant garden as a form of community initiatives in the Selang Pangeran area, Bahorok Subdistrict, Langkat Regency, North Sumatra Province in conserving medicinal plants. This initiative is also part of the communitys efforts to provide services to the community and document the knowledge of medicinal plants. Interviews and direct collection of medicinal plants found in the medicinal plants garden are carried out. In addition, also carried out recording the name of the area, making voucher specimens to determine the type and scientific name of the plant. For each of the plants found, its use and which parts are used from the plant are recorded. Documentation of several types of plants was also made to facilitate the identification process. A total of 34 types of medicinal plants were collected for information. It can be seen that community initiatives have succeeded in preserving medicinal plant resources, documenting the knowledge of medicinal plants, and transmitting knowledge of the use of medicinal plants.

Keywords
medicinal plants, medicinal plant garden, conservation strategies, community initiatives.

Topic
Botany

Link: https://ifory.id/abstract/JEGYme6nWwhK

Corresponding Author
Solichatul Afifah

Institutions
Department of Biology, Faculty of Mathematics and Natural Sciences, University of Malang

Abstract
Rheumatoid Arthritis (RA) is an inflammatory disease of the synovium. The key enzyme which role in RA is mPGES-1, which catalyzes conversion PGH2 into PGE2. PGE2 is the primary prostaglandin in inflammation when PGE2 binds to receptors PGE2, and it can activate the transcription factor. Data from WHO in 2010 depict that the prevalence of RA sufferers is relatively high. The synthetic drugs for RA commonly used are piroxicam and meloxicam, but has effect due to hepatoxics, so that a safe alternative which using an herbal madicine such as red betel. Red betel leaves contains terpenoid compounds such as β-amyrin, Spathulenol, Caryophyllene, and Humulene. Several previous studies reveal that terpenoid can inhibit prostaglandin biosynthesis such as terpenoid in Boswellia species and Salvia officinalis, which can inhibit mPGES-1. The purpose of this study is to predict potential of β-amyrin, Spathulenol, Caryophyllene, and Humulene terpenoid compounds in Red Betel as mPGES-1 inhibitor through Molecular docking, PA test, and ADMET test using software and web servers. The results showed four terpenoid compounds and mPGES-1 were on same binding site as drugs, and bound with enzyme through alkyl bond, while β-amyrin bound not only with alkyl bond but also hydrogen bond. The binding affinity of four terpenoid compounds were not significantly different from drugs. The potentials of antiinflammatory, antiarthritic, NSAID, transcription factor inhibitor and pharmacokinetic better than drugs. Based on the generated results, it can be concluded that β-amyrin, Spathulenol, Caryophyllene, and Humulene in Red Betel are potential for an antiinflammatory RA drug candidate.

Keywords
Rheumatoid Arthritis, mPGES-1, Virtual Screening

Topic
Bioinformatics

Link: https://ifory.id/abstract/ZmrWJwqt4MFG

Corresponding Author
Edwin Widodo

Institutions
1) Department of Physiology, Faculty of Medicine, Brawijaya University
*edwin[at]ub.ac.id
2) Department of Microbiology, Faculty of Veterinary Sciences, Brawijaya University

Abstract
Diabetes mellitus is a metabolic disorder that is characterized by chronic hyperglycemia, which is accompanied by damage, dysfunction of some organs and disturbance of the metabolism. In diabetes type II, there is a decrease of the ability of insulin to work in peripheral tissues (insulin resistance) and β cell dysfunction. As a result, the pancreas is unable to produce enough insulin to compensate for insulin resistance. Infection of Staphylococcus aureus in diabetes mellitus may worsen the condition. It can lead to bacteremia as well as increase the occurrence of inflammation. This research was aimed to know the molecular responses of rats (Rattus norvegicus) treated with streptozotocin and S.aureus via CD4 T cells and TGF-β levels. This research was Completely Randomized Design (RAL) experiment, with five groups of treatment. Group 1 was normal rats, Group 2 was bacteremia treatment with infection of S.aureus 10^8 CFU/mL, and three other groups were 45 mg/kg streptozotocin-induced diabetes with different level of S. aureus infection (10^5, 10^6 and 10^7 CFU/mL). Injections of streptozotocin were done intraperitoneally in high single dose (45 mg/kg). Blood glucose levels was measured after 2 days of STZ injection followed by Staphylococcus aureus injection intraperitoneally. The relative levels of CD4 T cells and TGF-β was measured by flowcytometry. The data was analyzed using One Way Analysis of Variance (ANOVA) (α = 0.05). The results showed an average CD4 levels were relatively experienced 6.9%, 7.9% and 3.5% increase in group 3, 4 and 5 respectively. The average relative levels of TGF-β were decreased 0.7%, 3.1% and 5.1% in group 3, 4 and 5 respectively. In conclusion, the relative levels of CD4 increased while the relative levels of TGF-β decreased in streptozotocin-induced diabetes rats infected with Staphylococcus aureus.

Keywords
CD4, TGF-β, Diabetes mellitus, Staphylococcus aureus

Topic
Biomedical Science

Link: https://ifory.id/abstract/4RULue3nv7AD

Corresponding Author
ATIKAH AMALIA

Institutions
Biology Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang, Indonesia

Abstract
It has been investigated that the prevalence of Rheumatoid Arthtritis (RA) is 0.5% -1.0% in general population worldwide. Inflammation arises because of prostaglandins, which are proinflammatory mediators enacted by the stimulus. The key enzyme in inflammation is cyclooxygenase-2. Flavonoids have various biological effects in mammalian cells carried out both in vitro and in vivo. This study was carried out to predict the potential of flavonoid group compounds as anti-inflammatory agents for rheumatoid arthritis through virtual screening using molecular docking methods. This method was employed to predict the potential of flavonoid compounds using web server PASS SERVER, predictions of the pharmacokinetic properties of flavonoid compounds including absorption, distribution, metabolism, excretion, and toxicity using pkCSM and molecular docking web servers to determine the interaction of COX-2 enzyme flavonoid compounds which was compared with control drugs. The results of this study indicated that flavonoid compounds (kaempferitrin, afzelin, and routine) could potentially replace the drug rofecoxib based on potential compounds, namely as anti-inflammatory, non-steroidal anti-inflammatory agents, antioxidants, and anti-carcinogenic. Flavonoid compounds had a decent ADMET profile. The compound had considerable activity as an anti-inflammatory agent based on its interaction with the COX-2 enzyme as indicated by the binding affinity value of ± -8.5 kcal/mol.

Keywords
Flavonoids, Inflammation, Molecular Docking

Topic
Bioinformatics

Link: https://ifory.id/abstract/NAByGmCu8Xxc

Corresponding Author
Azizatur Rahmah

Institutions
a) Islamic Univerity Maulana Malik Ibrahim Malang email : zizaquw[at]gmail.com
b) Balai Besar Penelitian Dan Pengembangan Tanaman Obat Dan Obat Tradisional email: ywidiyasis[at]gmail.com

Abstract
Centella asiatica is a popular plant that is currently the main claim for skin care ingredients that have the effect of accelerating the healing of zits and regenerating the skin. C. asiatica has a chemical component in the form of polyacetylenes, triterpenoids, asiaticosides, centellin, asiaticin and centellicin. The chemical components contained in C. asiatica have pharmacological effects in the form of antineoplastic, antiviral, antibacterial, antifungal, anti-inflammatory, antioxidant, anticonvulsant, antipsoriatic, anti-ulcer, wound healing, sedative, immunostimulant, cardioprotective, hepatoprotective, neuroprotective, antidiabetic, antidiabetic, and insecticidal . This many potential had made researcher explore the diversity of C. asiatica from various perspectives including DNA analysis. DNA profiling with SRAP has not been done, so this study becomes important data on C. asiatica. DNA profiling analysis of C. asiatica using SRAP with 8 primary combinations. Data was obtained from DNA isolation using the GeneJET Plant Genomic DNA Purification Mini Kit) or by modification. addition of PVP 2% of the total volume of lysis buffer A. Analysis using the Unweighted Pair method Method Group Using Aritmetic Method (UPGMA). Coordinate principle analysis (Principal Coordinate Analysis) of each individual. The data has been analyzed using a computer program (software) NTSYS 2.1, MVSP and PopGen 1.3 / GenAlex and other similar software. The results of the analysis showed that with SRAP marker C. asiatica formed 3 large clusters, cluster 1 had a 0.00 (0%) similarity coefficient, cluster 2 had a similarity coefficient value of 0, 12 (12%) and cluster 3 had a similarity coefficient value of 0.12 ( 12%). SRAP was able to determine the difference from 25 samples obtained from all over Indonesia.

Keywords
Centella asiatica, SRAP

Topic
Botany

Link: https://ifory.id/abstract/PagpHTCtBre9

Corresponding Author
Aulia Fahira

Institutions
1Department of Parasitology, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia.
2Department of Anatomical Pathology, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia.
3Medical Degree Program, Faculty of Medicine, Brawijaya University, Malang, East Java, Indonesia.

Abstract
RAS gene mutations, especially KRAS, are most common mutation in colorectal cancer. Mutations cause changes in conformation of KRAS protein, makes it unable to bind with RASGAP that works to turn KRAS off. The main chemotherapy drug for colorectal cancer is 5-fluorouracil (5-FU) which inhibits thymidylate synthase. 5-FU has many side effects, therefore it is necessary to consider a combination therapy with natural chemotherapy agents, one of which is lysenin, found in coelomic fluid from Lumbricus rubellus. The aim of this study was to determine the potential of lysenin bond with KRAS as a way of inhibiting the cancer pathway. This research is an in silico experimental study using PatchDock, FireDock, PyMOL, and LigPlot, while the molecular structures are taken from Pubchem and Uniprot databases. Result from molecular docking indicates that there was a bond between lysenin and KRAS with binding affinity score -14.51 kcal/mol, while RASGAP and KRAS has a binding affinity score 4.32 kcal/mol, but after lysenin binds to KRAS, the binding affinity score of this complex with RASGAP becomes -20.47 kcal/mol which was stronger. In conclusion, it was estimated that lysenin was able to become a bond stabilizer between KRAS and RASGAP, consequently KRAS can be turned off. This mechanism of lysenin which was different from 5-FU was expected to have a synergistic effect in inhibiting colorectal cancer.

Keywords
Colorectal cancer, KRAS, 5-fluorouracil (5-FU), lysenin, Lumbricus rubellus, molecular docking

Topic
Bioinformatics

Link: https://ifory.id/abstract/JbRQ86HVjxvG

Corresponding Author
Muhammad Fatoni

Institutions
Institut Teknologi Sepuluh Nopember

Abstract
Gold mining is the main source of waste tailings production that can pollute the environment. Gold phytomining is the process of extracting gold metal from the soil by a gold hyperaccumulator plant. In this study sunflower (Helianthus annuus) is used as the main agent of gold phytomining symbiosis with Arbuscular Mycorrhiza Fungi (AMF), Glomus sp. This study has two purposes. First, measuring the concentration of Au metal in sunflowers (Helianthus annuus) use symbiosis Glomus sp. Mycorrhiza, when accumulate gold metal. Second, determining the resistance of the stem height and number of sunflower (Helianthus annuus) leaves. The method used is through AAS and periodic measurements. The results obtain sunflower (Helianthus annuus) is able to accumulate gold. The highest concentration of Au metal is 137.81 mg/kg obtained at the treatment of 100 grams of mycorrhiza, while the lowest concentration of Au metal is 35.24 mg/kg obtained at the treatment of 0 gram mycorrhiza. The 40 grams of mycorrhiza has the most significant effect related to sunflower resistance (Helianthus annuus) when absorbing gold metal because it produces plants with a stem height of 13 cm and the highest number of leaves is 10 leaves.

Keywords
Sunflower (Helianthus annuus), Gold, Glomus sp., Mycorrhiza.

Topic
Botany

Link: https://ifory.id/abstract/2L3e6PzxQDZH

Corresponding Author
Eko Budi Minarno

Institutions
Department of Biology, Faculty of Science and Technology Maulana Malik Ibrahim State Islamic University Malang

Abstract
Emprit ginger (Zingiber officinale var. Amarum) is used by the people of Duwet Krajan Village, Tumpang District, Malang Regency, among others, for medicinal plants. The utilization of these plants is a local wisdom of the community. The purpose of this study was to analyze the use of emprit ginger as a medicinal plant by the people of Duwet Krajan Village, Tumpang District, Malang Regency. This research was conducted by survey method with semi-structured interview techniques and observations. Research data is categorized as the types of utilization, processing methods, compounding methods, methods of acquisition, and conservation efforts. 10 people respondents were determined using a purposive sampling method based on their knowledge of emprit ginger and their participation in training held by the Manpower Office. Analysis of the data was done using descriptive analysis techniques and literature studies. The results showed that 60% utilization is for the purpose of warming the body, treated aches of 10%, dizziness by 20%, colds by 30%, chills by 20% and relieving coughs by 100%. The method of processing is by making instant ginger powder by 70%, drying by 20%, and boiling at 10%. The way of compounding is by brewing without any additional ingredients by 50% and brewing with additional ingredients by 50%. The way to obtain the ginger is by buying 10% and cultivating in the field or yard by 90%. Conservation efforts are carried out by cultivating in the field or yard as a form of livelihood in the local community.

Keywords
Emprit ginger, Zingiber officinale var. Amarum, Duwet Krajan Village

Topic
Botany

Link: https://ifory.id/abstract/ZL4p32DeNxfT

Corresponding Author
Muhammad Zaki

Institutions
(1) Geophysical Engineering, UPN Veteran Yogyakarta, Jalan SKW 104 Lingkar Utara, Yogyakarta 55283, Indonesia
(a) wahyu.hidayat[at]upnyk.ac.id

Abstract
Wonogiri Dam is one of the largest dams in Indonesia, located ± 2 km south of the Wonogiri City, in the province of Central Java. Wonogiri Dam has a volume ± 400 million m3 with a surface area of 73,6 km2 which has many benefits such as for agriculture, tourism, and power plant. Wonogiri is a part of the East Java Southern Mountain Zone. There are many rocks types found at Wonogiri, such as volcanic breccias, andesite lavas, tuffs, and many igneous intrusive rocks of the Miocene Mandalika and Semilir Formations, unconformably underlie Quaternary volcanic rocks of Lawu and Merapi Volcanoes (Sutarto, 2013). This research aimed to determine Ground Shear Strain (GSS) value along main dam and the surrounding area and to predict phenomena based on GSS values. From dominant period (TG) value, we can predict site class based on the classification of Zhao et al (2004). The microtremor data was taken on 31 observation points which is divided from 14 observation points with 100 m spacing in main dam and 17 observation points with 1.000 m spacing in surrounding area from Wonogiri Dam. Microtremor data was analysed using Horizontal to Vertical Spectral Ratio (HVSR) method to get amplification factor and dominant frequency. Those data were used to determine the seismic vulnerability index (Kg). Kanai empirical equations was used to calculate Peak Ground Acceleration (PGA) value based on earthquake event on 27th of Mei, 2006 with a moment magnitude of 6,3 and and 11,8 km depth. Seismic vulnerability index and peak ground acceleration value are used to determine the GSS value. The results of this research showed that GSS value in research area was about 3,4 x 10-4 to 7,2 x 10-3. The phenomena that can happen were ground movement as the form of surface cracking and settlement. Seismic vulneribility index was below 20 (0,35 to 16,97) which means surrounding area from Wonogiri Dam and main dam have low-risk, but potential for damage to building is still possible. Along main dam area, we need to notice the point at 400m and 600m. The value of the dominant period in research area ranged from 0.07 to 1.11 second. Based on the classification of Zhao et al (2004), there are 3 classes of site class in the research area.

Keywords
Dam, Ground Shear Strain, Site Class.

Topic
Geophysics,Geomatics and Geochemistry

Link: https://ifory.id/abstract/VcXez6vJdmuH

Corresponding Author
Nur Aini

Institutions
a) Departement of Chemistry Education on Post Graduate Program, State University of Medan, Indonesia
*nurainibinibrahim[at]gmail.com
b) Lecturer in Department of Chemistry Education on Post Graduate Program, Stated University of Medan, Indonesia

Abstract
Abstract: The aim of this research is showing; 1) The differences in critical thinking skills of students taught using Problem based learning with those using conventional eXe-based learning; 2) The differences in the student ability critical thinking of chemistry who have low scientific attitudes and high scientific attitudes; 3) The Interaction between the Learning-Based Learning model and the level of scientific attitudes of students in influencing critical thinking skills of student. This research is done at SMA N 1 Rambah. The sample of research all of student at SMA class X at the first semeste. Intrument for measure the result of study from student critical thinking skills using a multiple choice and for measure of the scientific attitude is using questionnaire sheet. This research was conducted with the experimental methods. The sample was divided into two classes, where the experimental class learned with PBL using exe learning and the exe learning class learned with convetional using exe learning. Data were analyzed descriptively ang inferensial with the help of SPSS version 22 at significance level &

Keywords
PBL; scientific attitudes; critical thinking skills; eXe learning

Topic
Curriculum, Research and Development

Link: https://ifory.id/abstract/vzHaR7CFYhnB

Corresponding Author
Nangkula Utaberta

Institutions
1Halal Products Research Institute, Universiti Putra Malaysia
2Linton University College
3Department of Architecture, Faculty of Design and Architecture, Universiti Putra Malaysia
4Department of Architectural & Design Engineering, Faculty of Civil and Environmental Engineering, Universiti Tun Hussein Onn Malaysia
5School Of Architecture and Built Environment, UCSI University.

Abstract
To promote Malaysia as the most desired Islamic tourism hub in the world, it is significant to identify and popularize the uniqueness of Malaysia in terms of tourist spots, experience, facilities and Muslim friendly practices. Currently Malaysia as an Islamic tourism hub is in tough competition with similar hubs such as Turkey and UAE. Staying ahead in this race requires efficient -Rebranding- of the tourist spots and facilities i.e. the Islamic Architecture of Malaysia which can attract more tourists to choose Malaysia as their prime location for Islamic tourism. In general, Malaysia as a nation was developed in the richness of the cultural diversity and varies of influences. It is reflected with the wide range of architectural style that creating the colors and defining the uniqueness of Malaysian architecture style. In the micro context, one of the building typology which carrying this -unique spirit are mosque. Throughout the Malaysia, there are numbers of mosques architectural typologies had been identified, with the range of vernacular, colonial, modernism and up to modern contemporary architecture style. Malaysia has various mosques in the country and has adopted different architectural designs inspired by varying ethnic subcultures, periods of colonialism, foreign influence, technology utilization, and the political environment. In this research, three contemporary mosques selected. Generally, the architectural styles of the modern mosque can be classified into two categories. The first category is the modern styles which emphasize the advancement in building technology and engineering (i.e. Masjid Tunku Mizan Zainal Abidin). The second category of the modern mosque is the Islamic influences which incorporate the styles of many mosques found in Islamic countries including Turkey, the Middle East, and Northern Africa (i.e. Masjid Putra). This research will attempt to formulate framework in reevaluating the contemporary mosque of both types through identifying and documenting the unique attributes of these mosques as well as taking into account how the tourists perceive these attributes to prioritize Malaysia as their No. 1 Islamic tourism hub.

Keywords
Tourism, Uniqueness, Contemporary Malaysian Mosque.

Topic
Halal Lifestyle, Fashion, Travel and Tourism

Link: https://ifory.id/abstract/mMGv2TakNHtY

Corresponding Author
Nangkula Utaberta

Institutions
1Halal Products Research Institute, Universiti Putra Malaysia
2Linton University College
3Department of Architecture, Faculty of Design and Architecture, Universiti Putra Malaysia
4Department of Architectural & Design Engineering, Faculty of Civil and Environmental Engineering, Universiti Tun Hussein Onn Malaysia
5School Of Architecture and Built Environment, UCSI University

Abstract
To promote Malaysia as the most desired Islamic tourism hub in the world, it is significant to identify and popularize the uniqueness of Malaysia in terms of tourist spots, experience, facilities and Muslim friendly practices. Currently Malaysia as an Islamic tourism hub is in tough competition with similar hubs such as Turkey and UAE. Staying ahead in this race requires efficient -Rebranding- of the tourist spots and facilities i.e. the Islamic Architecture of Malaysia which can attract more tourists to choose Malaysia as their prime location for Islamic tourism. In general, Malaysia as a nation was developed in the richness of the cultural diversity and varies of influences. It is reflected with the wide range of architectural style that creating the colors and defining the uniqueness of Malaysian architecture style. In the micro context, one of the building typology which carrying this -unique spirit are mosque. Throughout the Malaysia, there are numbers of mosques architectural typologies had been identified, with the range of vernacular, colonial, modernism and up to modern contemporary architecture style. From the range of these styles, one of the styles that represent the uniqueness of Malaysia is traditional architecture mosque. It been designed and constructed with the philosophy and thoughts that been born by culture and the way of people-s life in that time. Traditional mosques in Malaysia are generally associated with the characteristic of Malay traditional architecture which can be seen majorly from the Malay traditional house physical characteristic. Build in the unique characteristic, Malacca traditional mosque represent the different characteristic from the norms of Malay traditional mosque. It is the manifestation of the influences and cultural coalition in Malacca as one of the major trading hub in Asia during that time. Despite the uniqueness and the richness of the Malacca traditional mosques architectural style, the intrinsic and extrinsic values of them are far away from the knowledge of the peoples, specifically the guidance of tourism parties which responsible to deliver the right information and the stories behind the mosques to the tourists. Hence, this research will attempt to formulate framework in reevaluating the Malacca Traditional Mosque through identifying and documenting the unique attributes of these mosques as well as taking into account how the tourists perceive these attributes to prioritize Malaysia as their No. 1 Islamic tourism hub.

Keywords
Tourism, Uniqueness, Malacca Traditional Mosque.

Topic
Halal Lifestyle, Fashion, Travel and Tourism

Link: https://ifory.id/abstract/YuHdv7xjJ2MW

Corresponding Author
Nangkula Utaberta

Institutions
1School of Architecture and Built Environment, FETBE, UCSI University, Cheras, Malaysia
2Halal Products Research Institute, Universiti Putra Malaysia, Selangor 43400
3Faculty of Built Environment, Linton University College, Negeri Sembilan, Malaysia

*Corresponding author E-mail: nangkulautaberta[at]gmail.com

Abstract
With the establishment of a new administrative center in Putrajaya, an opportunity to address and to reaffirm a national architectural identity was present. This research attempts to document and evaluate the design direction of administrative buildings in Putrajaya in response to the issue of establishing a national architectural identity. It will attempt to analyze the various inputs towards achieving the desired image, from the political, socio cultural as well as economic context. Additionally, it is crucial to understand the architectural identity thoughts and standpoint of the architect that was in charge of the design and implementation of the selected administrative building. This research uses a historical architectural interpretative methodology to analyze the building in place and aided with literature reviews, interviews with the relevant persons involved as well as on site direct observation and analysis of the building involved. The data obtained and presented reveals the thoughts that was the basis on forming the national architecture identity to an extent. The architects position in relation to achieving the design brief but at the same time, utilizing his or her reflection and background formation. The research discovers the architects design principles were to emphasize the local and Islamic characteristics to highlight the role of Islam within the new administrative center of Malaysia. The resulting outcome of this research will provide an understanding on how to critically engage in addressing architectural issues that forms a national architecture identity.

Keywords
National architecture identity, Putrajaya, Administrative building, Menara Seri Wilayah, Kementerian Wilayah Persekutuan

Topic
Halal Lifestyle, Fashion, Travel and Tourism

Link: https://ifory.id/abstract/xFHaRh7wyKjL

Corresponding Author
Intan Nur Balqis Mohd Khalid Wong

Institutions
1. Halal Product Research Institute, Universiti Putra Malaysia, Putra Infoport, 43400 UPM Serdang, Selangor, Malaysia

2. Department of Agriculture Technology, Faculty of Agriculture, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
*Correspondence: ssalwaag[at]upm.edu.my

3. Department of Land Management, Faculty of Agriculture, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia

4. Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia

Abstract
Pereskia bleo (Kunt) DC is a leafy cactus species traditionally used by locals in Malaysia for treatments of various ailments known to be due to its high total phenolic content (TPC). There are a number of procedures in extracting TPC from plant materials. This paper reports a study conducted on maximizing microwave-assisted extraction of TPC, expressed as gallic acid equivalent (GAE), from leaves of the species using one variable at a time method (OVAT). The study establishes that the best solvent for extraction of TPC from leaves was ethanol with concentrations ranging from 20-40%. Solvent to solid ratio was set at 1:30. The best extraction time and microwave power to obtain high yield of TPC ranged from 30 to 60 seconds and from 40W to 50W, respectively. The study presents a simple and efficient non-conventional method of extraction of TPC from Pereskia bleo simplifying extraction procedure in an attempt at exploiting the potentials of the species as a source novel therapeutic agent. In the future, anti-inflammatory activities of Pereskia bleo will be investigated and the preliminary study on the extracts is for future halal and organic formulation.

Keywords
Pereskia bleo, one variable at a time, microwave-assisted extraction, total phenolic compound.

Topic
Halal Science and Technology

Link: https://ifory.id/abstract/2VHeNhdWbkAq

Corresponding Author
Siti Atikah binti Zulkifli

Institutions
1)Halal Products Research Institute,
2)Department of Agriculture Technology, Faculty of Agriculture,
*ssalwaag[at]upm.edu.my
3)Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences,
4)Department of Land Management, Faculty of Agriculture,
Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.

Abstract
The purpose of the present study is to evaluate whether ethanol concentrations (20-95% v/v), extraction time (30-240 min) and extraction temperature (20-80℃) will affect the antioxidative polyphenols extraction utilising one variable at a time (OVAT) method. Total phenolic content (TPC), total flavonoid content (TFC) were used to determine the polyphenolic amount while 2,2-Diphenyl -1-picrylhydrazyl (DPPH) radical scavenging activity was used for evaluating the primary antioxidant capacity of red pitaya defatted seed (RPDS). All various extracting conditions studied showed a significant effect at p < 0.05 on the amount of phenolic and antioxidant activity. The optimise conditions determined for extracting phenolic RPDS were 80% ethanol for 60 min at 80 ℃, which correspond to the value of 104.76 mg GAE/g sample for TPC, 10.76 mg QE/g sample for TFC with 89.36% inhibition of DPPH radical. This study suggests that RPDS extract have the potential to be utilised as halal and natural antioxidants agent in the future product formulation.

Keywords
antioxdiant activity, phenolic content, red pitaya defatted seed, temperature, time.

Topic
Halal Food, Pharmaceutical, and Cosmetics Manufacturing

Link: https://ifory.id/abstract/hwu8t3F9rVbM

Corresponding Author
Andro Agil Nur Rakhmad

Institutions
Universitas Negeri Malang

Abstract
This study aims to describe the relationship between Islamic financial institutional literacy and the preferences of Islamic financial institutions. The institutional literacy of Islamic finance is explained by indicators of knowledge of the terms sharia, sharia substance and sharia institutions. The subject of this study were students of the economic faculty of the State University of Malang from three majors : Management, Accounting and Development Economics. Samples were taken randomly and proportionally from the three majors. The results of the study show that most students of economic faculties do not yet understand the basic principles of Islamic finance. Most of the students also have literacy that is sufficient about cooperative institutions. Economic students have a good preference for sharia cooperatives. Islamic financial institution literacy influences the preference of sharia financial institutions.

Keywords
Literacy, Preferences, Students, Sharia Cooperatives.

Topic
Islamic Banking, Finance, Insurance, and Sharia Accounting

Link: https://ifory.id/abstract/8JWzTKr3MdRZ

Corresponding Author
Andi Fikri Zaidan

Institutions
Universitas Negeri Malang

Abstract
Human resources is one of the elements that determine the success of an institution of higher education. The greatest responsibilities are grasped to lecturers because they have a very important role as the spearhead of the overall implementation of the teaching process. Therefore institution must pay attention to job satisfaction of the lecturer. There are many factors that affect job satisfaction. There are workload and job stress. The purpose of this study to determine: (1) Description of workload, job stress, and job satisfaction of the lecturer of State University of Malang; (2) The influence of workload directly and indirectly on job satisfaction through job stress. In this research, the method used is quantitative research methodology. The sample used in this research amounted to 176 respondents. The sampling technique used is proportionate stratified random sampling and use validity and reliability test for data testing tecniques. The method of analysis of the data used is path analysis. Based on the analysis to the lecturers of State University of Malang found that: (1) Description of the lecturers of State University of Malang have have a fairly high of workload, job stress of lecturer in low category, and job satisfaction of lecturer in high category; (2) workload doesn-t have a significant effect on job stress of lecturer of State University of Malang; (3) there is a negative and significant influence of workload on job satisfaction of lecturer of State University of Malang; (4) There is a negative and significant influence of job stress on job satisfaction of lecturer of State University of Malang; (5) job stress doesn-t mediate between workload and job satisfaction of lecturer of State University of Malang. Based on the results of the study, the researcher suggests: (1) For institutions to be able to maintain job satisfaction of the lecturers to be able to work comfortably. So that can minimize the stress of most lectures; (2) For institution to fix the facilities that are damaged or broken. There may also be new facilities, such us a gym, a pantry, or a special room to relax. So they can get a better interaction among lecturers with a more comfortable atmosphere as well; (3) For lecturers who feel the stress high enough to be able to more enjoy the work, so they can further minimize the effects of work stress; (4) For further researchers who want to research the workload of lecturers, to find ways to be more able to reveal the true reality that happened. So that the results of research can be better describe the real condition of State University of Malang.

Keywords
Workload, Job Stress, Job Satisfaction

Topic
Management, Organization, Leadership and IT

Link: https://ifory.id/abstract/xZFYTyv7zPQb