Indonesia Conference Directory

Corresponding Author
Nurrahmi Umami

Institutions
Oral Biology Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
Orthodontic Department, Faculty of Dentisty, Hasanuddin University, Makassar, Indonesia

Abstract
Abstract Objective: The aim of this study was to determine the effectiveness of topically administered corn silk extract to reduce blood glucose level and its effect on hyperglycemic related periodontal tissue inflammation. Method: Fifteen male Wistar rats with an initial weight of 150 gram were included in this study. Alloxan was used to induce diabetes and 5-0 silk ligatures to induce periodontal tissue inflammation. Blood glucose level was analyzed before and after induction, 3 days and 7 days after administration. Degree of periodontal tissue inflammation was examined with the histopathology test. Statistical analysis was conducted using the student t-test. Results: Blood glucose level in F1 group was unstable (p=0.0583>p=0.05), whilst both F2 and F3 group showed stable blood glucose decrease (F2: p=0.0086p=0.05; F2: p=0.423>p=0.05). Conclusion: Topically administered corn silk extract was effective to reduce blood glucose level and hyperglycemic related periodontal tissue inflammation in alloxan-induced diabetic rats

Keywords
Alloxan; Corn silk extract; Diabetes Mellitus; Inflammation; Periodontal tissue

Topic
Nutrition and Quality of life

Link: https://ifory.id/abstract/C4am9MxJpjcV

Corresponding Author
Nurrahmi Umami

Institutions
Department Oral Biology, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Abstract
Abstract Objective: The aim of this study was to determine the effectiveness of topically administered corn silk extract to reduce inflammation degree in periodontitis. Methods: Material used in this research was 40 days old corn silk extract. Twelve male Wistar rats (Rattus novergicus) with the initial weight of 150 gram were used as experimental model animals. The rats were then divided into four groups with 3 rats each. The animals were induced with 5-O silk ligature wire for seven days. After that the silk ligatures were removed and each group were given treatments according to their group for seven days. Results: F3 shown the best anti-inflammation effect with mild inflammation in each sample (p<0.05). Whereas in F1 and F2 each sample had moderate inflammation (F1, F2: p>0.05). Conclusion: Topically administered corn silk extract (Zea mays. l.) are effective to reduce the degree of inflammation in periodontitis.

Keywords
Corn silk extract; Inflammation; Periodontitis

Topic
Herbal medicine

Link: https://ifory.id/abstract/TjedkF8Z69Jn

Corresponding Author
Nurrahmi Umami

Institutions
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Abstract
Abstract Objective: Cleft lip and palate are incomplete development of the lips and palate during the fetus formation. The cariogenic bacteria were significantly increased in cleft lip and palate patients. The aim of this study compared the amount of pre and post-operative bacteria in patients with cleft lip and cleft lip and palate. Methods: This study was an observational laboratory with prospective design study. A sample of 20 people consisting of two groups, 10 people with cleft lips, and 10 people with cleft lip and palate with specified inclusion and exclusion criteria. The sampling of bacteria on the dorsal tongue before and after surgery. Further, bacterial colonies were counted in a laboratory. Processing and data analysis using SPSS version 22 Results: Data analysis showed the statistical differences between pre and postoperative bacteria number, where was in cleft lip patients and cleft lip and palate showed a significant decrease of bacteria number (p <0.05) Conclusion: Pre and post-operative bacterial colonies of the patients with cleft lip and palate were more than cleft lip patients and the number of bacterial colonies was reduced after surgery.

Keywords
Bacteria; Cleft lip and palate; Pre and postoperative.

Topic
Information, technology, and women

Link: https://ifory.id/abstract/mur4DLdBpVYP

Corresponding Author
Nurrahmi Umami

Institutions
Oral Medicine Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
Oral Medicine Department, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia

Abstract
Abstract Objective: To prove the increasing of salivary HBD2 level in DMT2 patients, and to analyze its correlation with the number of colonies of C.Albicans species in the oral cavity DMT2 patients. Methods: This study was an analytic observational with Cross Sectional design and was done by taking saliva of DMT2 patients by spitting method to calculate HBD2 level and test with ELISA kit. To find out the number of C.Albicans colonies, a swab method was performed on the patients mucosa to be identified under a microscope and developed using 3 methods: DIRECT, Carbohydrate fermentation test and urea hydrolysis test. Results: ELISA test results showed that HBD2 levels increased significantly in the saliva of DMT2 patients compare the control (non DM) group, whereas the number of C.Albicans colonies did not differ significantly between the groups. Conclusion: HBD2 levels in saliva of DMT2 patients increased compared with non-DM samples, and the number of C.Albicans colonies found over 100 CFU in three sample groups.

Keywords
Candida; Diabetes; Defensins

Topic
Nutrition and Quality of life

Link: https://ifory.id/abstract/ygdEnuU7N6kv

Corresponding Author
Nurrahmi Umami

Institutions
Conservative Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia.

Abstract
Abstract Objective: The objective of this study was to determine the effectivity of Haruan fish (Channa Striata) extract which added calcium hydroxide to ALP levels in the odontoblast cell line. Methods: The study used a posttest only control group design. Odontoblast MDPC-23 cell line which distributed in 96-well microplates is divided into 8 groups. ALP levels were measured by ELISA kit. Data were analyzed statistically using ANOVA statistical test, followed by Bonferronis post-test. Results: The ALP level in the odontoblast cell line in Haruan fish extract that added with calcium hydroxide increased compared to the control. At a concentration of 25 µg/ml = 208.37 µg/ml, a concentration of 50 µg/ml = 219.04 µg/ml, a concentration of 100 µg/ml = 282.93 µg/ml and differed significantly from the control group. Conclusion: The effect of Haruan fish extract added with calcium hydroxide increase the ALP level in odontoblast cell line as concentration increases.

Keywords
Alkaline Phosphatase; Haruan Fish (Channa Striata); Odontoblast Cell Line

Topic
Occupational and women

Link: https://ifory.id/abstract/mCV9t4EJWUcy

Corresponding Author
Nurrahmi Umami

Institutions
Prosthodontic Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
bPostgraduate Professional Education Student of Prosthodontic Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Abstract
Abstract Objective: This research aimed to determine the relationship between playing the violin and the severity of TMD, as well as the maximum pressure on the chin rest which is within safe limits while playing the violin, to prevent the occurrence of TMD. Methods: The 20 violin players of OSUI Mahawaditra and MYSO orchestra were undergoing the examination and interview. Measurement of the pressure on the chin rest was done by using a flexi force device that is attached to the chin, which will measure the chin pressure on the instrument (N). Results: The highest maximum pressure is 15.157 N, while the lowest maximum pressure is 0.126 N. The highest average pressure is 6.203 N and the lowest average pressure is 0.025 N. Conclusion: There is a strong relationship between chin pressure on the chin rest and TMD conditions in the violinist. There is no relationship between the frequency and duration of violin training with TMD conditions in violin players.

Keywords
Chin pressure; Temporomandibular disorders; violin players.

Topic
Information, technology, and women

Link: https://ifory.id/abstract/wfcbkeYtPArQ

Corresponding Author
Hendy Suhendy

Institutions
STIKes Bakti Tunas Husada Tasikmalaya

Abstract
Golongan senyawa fenol dan flavonoid pada umbi dua varietas ubi jalar yang diekstraksi dengan metode panas merupakan kontributor utama aktivitas antioksidan. Senyawa fenol dan flavonoid dipengaruhi oleh adanya pemanasan. Penelitian dilakukan untuk mengetahui pengaruh suhu ekstraksi terhadap fenol dan flavonoid total dua varietas umbi ubi jalar. Penelitian diawali dengan pengumpulan dan pembuatan simplisia dua varietas umbi yaitu umbi kulit luar berwarna ungu, bagian dalam berwarna ungu (UU) dan umbi kulit luar berwarna ungu, bagian dalam berwarna orange (UO). Simplisia diekstraksi menggunakan refluks dan maserasi dengan pelarut etil asetat sehingga diperoleh empat ekstrak yaitu ekstrak etil asetat umbi ubi jalar ungu-ungu maserasi (UUM), ungu-ungu refluks (UUR), ungu-orange maserasi (UOM) dan ungu-orange refluks (UOR). Fenol total dihitung menggunakan metode Folin Ciocalteu sedangkan flavonoid total menggunakan metode Chang. Fenol total ekstrak etil asetat UUM, UUR, UOM dan UOR secara berturut-turut adalah 7,50; 6,79; 4,85 dan 5,87 (g GAE/100 g). Flavonoid total ekstrak etil asetat UUM, UUR, UOM dan UOR secara berturut-turut adalah 16,24; 19,84; 9,65 dan 16,50 (g QE/100 g). Perbedaan suhu ekstraksi hanya mempengaruhi flavonoid total pada umbi ubi jalar UU dan UO. Refluks adalah metode yang paling baik untuk menyari senyawa-senyawa flavonoid umbi UU dan senyawa-senyawa fenol dan flavonoid umbi UO.

Keywords
Umbi, Fenol, Flavonoid, Ekstraksi, Ipomoea batatas

Topic
Farmakognosi dan Fitokimia

Link: https://ifory.id/abstract/FTm9XGZqgAjb

Corresponding Author
Nurrahmi Umami

Institutions
Oral Biology Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
Prosthodontics Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Abstract
Abstract Objective: To determine and compare measurement results of setting time and viscosity on alginate impression materials made of brown algae Sargassum sp. and Padina sp Methods: This study was an observational study with cross sectional design. Samples were sodium alginate extracted from brown algae Sargassum sp. and Padina sp. obtained from Punaga waters, South Sulawesi. Sample was formulated into irreversible hydrocolloid impression material, then measured for its setting time and viscosity. Results: Setting time of impression material made of Sargassum sp was 5.30 while that of Padina sp was 4.40. Based on ANSI / ADA No. 18/1992, these results were classified as alginate regular setting type. Viscosity of impression material made of Sargassum sp was 9760 while that of Padina sp was 9200 cps. Based on SIGMA 2008, these results were classified between medium and high viscosity types. Conclusion: Brown algae Sargassum sp. and Padina sp. has the potential to be one of the basic ingredients for manufacturing dental impression materials.

Keywords
Brown algae; Padina sp; Sargassum sp; Setting time; Viscosity.

Topic
Occupational and women

Link: https://ifory.id/abstract/mXR3nVYxhtDj

Corresponding Author
Alfi Hudatul Karomah

Institutions
Divisi Kimia Analitik, Departemen Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, IPB University, Bogor

Abstract
Sambiloto (Andrographis paniculata) merupakan tanaman obat yang banyak digunakan oleh masyarakat Indonesia. Aktivitas biologis pada sambiloto dipengaruhi oleh komposisi metabolit didalamnya. Komposisi metabolit tersebut dapat dipengaruhi oleh beberapa faktor, salah satunya bagian tumbuhan yang digunakan. Penelitian ini bertujuan untuk mengidentifikasi senyawa metabolit ekstrak daun dan batang sambiloto menggunakan LC-MS/MS dan mengklasifikasikan dengan PCA. Sampel batang dan daun dipisahkan dan diekstraksi menggunakan metode sonikasi dengan pelarut etanol 70%. Sebanyak 31 senyawa metabolit teridenfikasi dalam ekstrak batang dan daun sambiloto, yang terbagi ke dalam golongan asam fenolat, diterpen lakton, dan flavonoid. Senyawa metabolit tersebut diklasifikasikan menggunakan PCA. Berdasarkan hasil klasifikasi, setiap ekstrak terkelompok dalam kelas batang dan daun dengan total PC 92%.

Keywords
LC-MS/MS, PCA, sambiloto, senyawa metabolit

Topic
Teknologi Panen dan Kontrol Kualitas

Link: https://ifory.id/abstract/tYxMd2agReyr

Corresponding Author
Nurrahmi Umami

Institutions
Oral Biology Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
Prosthodontic Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
Dental Hospital, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Abstract
Abstract Objective: The aim of this study was to explore the potential of brown algae (Padina sp) by measuring its compressive and tensile strength as a preparation step for making standardized dental impression materials from sodium alginate Padina sp. Methods: This study was an quasi experimental study with a one-shot case design. Brown algae were taken from the waters of Punaga and Puntondo, Takalar. Sodium alginate was extracted from algae then mixed with other compositions to form alginate impression material. Compressive and tensile were tested using Point Load Test. Results: Compressive strength of impression material made of Padina sp were higher than that of standard impression material with pressure mean 0.011 Mpa and 0.009 Mpa. Mean of tensile strength measurement was 0.003 Mpa. Conclusion: Mean compressive and tensile strength of impression material made of Padina sp were still relatively weak.

Keywords
Nurlindah Hamrun

Topic
Occupational and women

Link: https://ifory.id/abstract/JtMqpAVjGzne

Corresponding Author
Umi Cahyaningsih

Institutions
1) Fakultas Kedokteran Hewan,Institut Pertanian Bogor,
Bogor
2) Pendidikan Biologi, FKIP, Universitas Khairun, Ternate

Abstract
Leukosit terdiri dari limfosit, monosit, neutrofil, eosinofil dan basofil yang merupakan sel darah putih berfungsi sebagai salah satu sistem pertahanan tubuh. Adanya Plasmodium dapat mengganggu pertahanan tubuh. Malaria pada mencit disebabkan oleh Plasmodium berghei yang dapat digunakan sebagai model untuk penelitian malaria pada manusia. Saat ini tanaman Artemicia annua sebagai antimalaria tetapi sudah mulai resisten. Oleh karena itu perlu mencari alternatif pengganti untuk obat antimalaria. Cengkeh varietas afo merupakan cengkeh tertua di dunia terdapat di Maluku Utara, secara in vitro dapat menghambat pertumbuhan Plasmodium. Tujuan penelitian ini untuk mengetahui persentase jenis leukosit pada mencit yang diinfeksi Plasmodium berghei dan diberi fraksi cengkeh varietas afo. Penelitian ini menggunakan 25 ekor mencit (Mus musculus) yang diinfeksi dengan Plasmodium berghei 1x106 dan dibagi menjadi 5 kelompok perlakuan, yaitu 1) kontrol negatif (tidak diobati), 2) kontrol positif (diberi Piperaquine), 3) kelompok P25 (diberi fraksi dosis 25 mg/kg BB), 4) kelompok P50 (dosis 50 mg/kg BB), dan 5) kelompok P100 (dosis 100 mg/kg BB). Mencit diberi fraksi etil asetat cengkeh varietas afo selama empat hari dan diberikan 24 jam setelah mencit diinfeksi P. berghei. Darah diambil pada bagian ujung ekor mencit setiap 24 jam sejak hari ke 0 sampai hari ke 7. Preparat ulas darah dibuat menggunakan pewarnaan Giemsa, kemudian diperiksa menggunakan mikroskop dengan pembesaran 1000 kali untuk menghitung persentase jenis leukosit. Hasil penelitian ini menunjukan pada hari ke 4 dan ke 5 setelah infeksi, perlakuan P50 dan P100 terjadi penurunan persentase neutrofil karena fraksi cengkeh mengandung karyofilen yang dapat menghambat pertumbuhan Plasmodium. Persentase limfosit meningkat pada perlakuan P50 dan P100 karena fraksi cengkeh ini mengandung flavonoid yang dapat meningkatkan proliferasi limfosit. Pemberian fraksi etil asetat cengkeh varietas afo mempengaruhi nilai persentase neutrofil dan limfosit pada mencit yang di infeksi Plasmodium berghei.

Keywords
Leukosit, fraksi etil asetat cengkeh varietas afo, Plasmodium berghei

Topic
Farmakologi dan Klinik TOOT

Link: https://ifory.id/abstract/LgUvxfBh3aEu

Corresponding Author
Nurrahmi Umami

Institutions
Public Dental Health Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia.
Periodontology Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia.

Abstract
Abstract Objective: This study aimed to define the effect of Gabus extract on the healing of Wistar rat induced periodontitis through histopathological examination. Methods: The study design used post-test with control group design, with two sample groups. Each sample group would be sacrificed and histopathological examination was performed to calculate the number of fibroblasts. Twenty-four Wistar mice with health conditions in the early stages were induced by periodontitis using a combination of silk ligature and Porphyromonas gingivalis bacteria. The slide observed using a microscope with 400x magnification to count of fibroblasts cell of each group. Results: Two-way ANOVA test and t-test produced significant differences [p<0.05] between the treatment groups of Gabus extract and the control group. Conclusion: Gabus extract could increase the number of Wistar rat fibroblasts induced by periodontitis.

Keywords
Channa Striata; Fibroblast; Gabus Extract; Periodontitis

Topic
Nutrition and Quality of life

Link: https://ifory.id/abstract/vqMJzPgnKj6Y

Corresponding Author
Nur Asni Setiani

Institutions
a) Sekolah Tinggi Farmasi Indonesia
Jalan Soekarno Hatta No. 354, Bandung 40266, Indonesia
*nur.asni[at]stfi.ac.id
b) RHIN Biotechnology
Jalan Sekar Kedaton no.10, Bandung 40252, Indonesia

Abstract
Tin (Ficus carica L.) merupakan tanaman obat yang memiliki banyak aktivitas farmakologi. Namun, produktivitasnya masih tergolong rendah. Kultur jaringan menjadi alternatif budidaya tanaman tin tanpa merubah kandungan metabolit sekunder. Optimasi dapat dilakukan dengan memodifikasi media pertumbuhan pada tahap multiplikasi. Penelitian ini bertujuan untuk mengetahui pengaruh kombinasi BAP (Benzyl Amino Purin) dan NAA (Naphthalena Acetid Acid) terhadap pertumbuhan tunas tanaman tin dan mengetahui kandungan metabolit sekundernya. Eksplan tin ditumbuhkan pada 9 kelompok media, yaitu kontrol MS0, MS0 yang ditambahkan BAP 0,5 mg/L+NAA (0,1;0,2;0,3;0,4 mg/L), serta BAP 1 mg/L+NAA (0,1;0,2;0,3;0,4 mg/L). Pengamatan dilakukan dengan melihat warna eksplan, mengukur panjang eksplan, jumlah tunas, jumlah daun, dan jumlah akar selama 4 minggu. Eksplan tin kemudian dimaserasi menggunakan etanol 96% dan dilakukan penapisan fitokimia pada ekstraknya. Data dianalisis menggunakan ANOVA. Pada minggu ke-4 diperoleh panjang eksplan terbaik 3,16cm (BAP 1 mg/L + BAP 0,1 mg/L), jumlah Tunas terbaik 10,66 (BAP 1 mg/L + NAA 0,1 mg /L), jumlah daun 8,66 (BAP 1 mg/L + NAA 0,1 mg/L) dan jumlah akar 2,33 (BAP 1 + NAA 0,2 mg/L). Konsentrasi optimum terhadap multiplikasi tanaman Tin yaitu dengan penambahan BAP 1 +NAA 0,1 mg/L yang memiliki perbedaan bermakna dalam setiap pengamatan kuantitatif dibandingkan dengan kelompok kontrol. Hasil penapisan fitokimia ekstrak etanol eksplan tanaman Tin menunjukkan adanya senyawa golongan alkaloid, flavonoid, fenolat, tanin, monoterpen dan seskuiterpen dan saponin.

Keywords
Tin, BAP, NAA, multiplikasi, eksplan

Topic
Budidaya Tanaman Obat

Link: https://ifory.id/abstract/24MgyHpZLAVk

Corresponding Author
Nurrahmi Umami

Institutions
Periodontology Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Abstract
Abstract Objectives: The aim of this report was to describe the management of periodontitis with hypercementosis. Methods: A 30-year-old male patient was referred from the Department of Conservation with complaints of pain during root canal filling. The tooth was traumatized 3 years ago. An intraoral assessment showed teeth

Keywords
Hypercementosis; Periodontitis; Regenerative treatment

Topic
Nutrition and Quality of life

Link: https://ifory.id/abstract/AfP4agGFXhKw

Corresponding Author
Erna Cahyaningsih

Institutions
Laboratorium Farmasi Bahan Alam, Program Studi DIII Farmasi, Fakultas Farmasi Universitas Mahasaraswati, Denpasar

Abstract
Tanaman Undis/Cajanus cajan (L.) Millsp dari suku leguminosae adalah salah satu tanaman yang bijinya dikosumsi di Bali berpotensi sebagai antioksidan sedang kulit buah belum banyak digunakan. Penelitian ini bertujuan mengetahui kandungan flavonoid total dan aktivitas antioksidan ekstrak etanol kulit buah Undis (Cajanus cajan (L.) Millsp). Ekstraksi dilakukan secara maserasi menggunakan pelarut etanol 80%. Penentuan kadar flavonoid total menggunakan spektrofotometri UV-Vis dan pengujian aktivitas antioksidan dilakukan dengan metode DPPH menggunakan spektrofotometri UV Vis. Berdasarkan hasil diperoleh nilai IC50 sebesar 60.3 ppm, yang menunjukkan ekstrak etanol kulit buah Undis dikatagorikan dalam antioksidan kuat. Hasil perhitungan kandungan flavonoid total dalam kulit buah undis 1,70  0,14 gram dalam 100 mg ekstrak.

Keywords
Cajanus cajan (L.) Millsp, antioksidan, DPPH, ekstrak etanol, Spektrofotometri UV-Vis.

Topic
Farmakognosi dan Fitokimia

Link: https://ifory.id/abstract/bPBqkZWVCFLd

Corresponding Author
Nurrahmi Umami

Institutions
Orthodontics Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
Oral Biology Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Abstract
Objective: The study aimed was to assess the three smile components on facial types of Senior High School students in Makassar, Indonesia. Material and Methods: The study was conducted at three Senior High Schools in Makassar. The subjects involved 198 students, 14-17 years old, consisting of 80 males and 118 females. Each subject was photographed while smiling from the frontal direction. The images were measured with Adobe Photoshop CS6 program to determine the facial type and the lip line, smile arc, and smile symmetry. The data was analyzed using Chi-square statistical test. Results: the percentage of medium lip lines was highest in all facial types and gender. There was no significant relationship between the facial type and gender with lip line. There was no significant relationship between the facial types and the smile arc but there was a significant relationship between the gender and the smile arc. Conclusion: Most of Senior High School students in Makassar have mesofasial type and medium lip line. There was a significant relationship between gender and smile arc and between gender and smile symmetry.

Keywords
Facial type; Smile components; Young adult

Topic
Information, technology, and women

Link: https://ifory.id/abstract/NC7hbP4zwM9D

Corresponding Author
Mumpuni Nur Izzati

Institutions
(1) Departemen Kimia, IPB University, Bogor, Indonesia
*mra.ipb.ac.id
(2) Departemen Statistika, IPB University, Bogor, Indonesia

Abstract
Temu lawak (Curcuma xanthorriza) merupakan tanaman obat yang diketahui memiliki efek farmakologis dengan efek samping yang rendah. Kunyit (Curcuma longa) dapat menghasilkan warna yang mirip dengan sampel temu lawak sehingga berpotensi menjadi bahan pemalsu pada sampel temu lawak terutama jika sudah disajikan dalam bentuk serbuk. Penelitian ini bertujuan mengembangkan metode analisis unutk autentikasi sampel temu lawak dari kunyit dengan konsentrasi pemalsu 0.5 ppm dan 1 ppm. Temu lawak dan kunyit murni diekstraksi dengan pelarut etanol 1:10 menggunakan metode ultrasonikasi selama 40 menit. Ekstraknya kemudian dipekatkan dengan pemutar uap dan pengering beku. Sampel pemalsu dibuat dengan mencampurkan ekstrak temu lawak murni dengan ekstrak kunyit pada konsentrasi pemalsu 0.5 ppm dan 1 ppm. Serapan larutan diukur pada panjang gelombang 200-800 nm dengan spektrofotometer ultraviolet-tampak dan pada bilangan gelombang 4000-400 cm-1 dengan spektrofotometer FTIR. Analisis multivariat menggunakan analisis parsial kuadrat terkecil-analisis diskriminan, analisis komponen utama-analisis diskriminan linear dan SIMCA dilakukan terhadap fusi data kedua rentang panjang gelombang. Analisis parsial kuadrat terkecil-analisis diskriminan dan analisis komponen utama-analisis diskriminan linear, belum mampu mengautentikasikan sampel pemalsu, namun analisis menggunakan SIMCA mampu mendeteksi adanya perbedaan antara temu lawak murni dengan sampel pemalsu baik itu pada konsentrasi 0.5 ppm maupun 1 ppm.

Keywords
autentikasi, fusi data, kemometri, temu lawak.

Topic
Teknologi Panen dan Kontrol Kualitas

Link: https://ifory.id/abstract/U47fBC6xpzjV

Corresponding Author
Nurrahmi Umami

Institutions
Pediatric Dentistry Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
Pediatric Dentistry Department, Faculty of Dentistry, Padjajaran University, Makassar, Indonesia

Abstract
Abstract Objective: To determine antibacterial potency in water fraction, n-hexane fraction and ethyl acetate fraction of red fruits against Streptococcus mutans ATCC 25175. Methods: This study was an experimental laboratory with true experimental design. The stages of the study included collecting samples, maceration, partitioning using water, n-hexane, and ethyl acetate solvents and testing the antibacterial activity of Streptococcus mutans. Results: The results of the study showed inhibitory zone of ethyl acetate fraction with concentrations 20% and 40%, 13.0 mm and 12.4 mm respectively, while inhibitory zone of water fraction, n-hexane and ethyl acetate with concentration of 10% does not exist or is worth 0.0 mm. Positive controls showed inhibition zone with an average of 21.2 mm in all three concentrations. The MIC and MBC was 0.312% and 0.625% respectively. Conclusion: Antibacterial potency of red fruit ethyl acetate fraction was higher than water fraction and n-hexane fraction against Streptococcus mutans ATCC 25175.

Keywords
Dental caries; Ethyl acetate fraction; n-hexane fraction; Red fruit; Water fraction

Topic
Nutrition and Quality of life

Link: https://ifory.id/abstract/Eeg4NB69Lvzb

Corresponding Author
Nur Fajriah Shoffiyanti

Institutions
Fakultas Farmasi dan Sains Universitas Muhammadiyah Prof. DR. Hamka, Islamic Center,
Jalan Delima II/IV, Perumnas Klender 13460, East Jakarta, Indonesia

Abstract
Tanaman alpukat (Persea americana Mill.) adalah tanaman yang dimanfaatkan di Indonesia secara tradisional untuk mengobati diabetes mellitus, khususnya bagian daun. Penyakit ini ditandai dengan gejala hiperglikemia, suatu keadaan dengan kadar glukosa yang melebihi batas normal. Penghambatan α-amilase pada saluran cerna dan konsumsi bahan aktif antioksidan merupakan salah satu cara untuk mengatasi kedaan hiperglikemia. Pada penelitian ini dilakukan pengujian aktivitas dari ekstrak etanol 70% daun alpukat dalam menghambat enzim α-amilase dan besar aktivitas antioksidan yang dihasilkan. Pengujian dilakukan dengan menggunakan spektrofotometer UV-Vis pada panjang gelombang 524 nm yang selanjutnya dibandingkan dengan standar, akarbose. Hasil penelitian menunjukan ekstrak etanol daun alpukat memiliki IC50 sebesar 139.1 µg/ml, sedangkan akarbose memiliki IC50 sebesar 42.7 µg/ml. Ekstrak etanol 70% daun alpukat memiliki potensi relatif sebesar 0,3 kali dibandingkan akarbose. Sedangkan pada hasil uji antioksidan didapatkan jika besar IC50 adalah 291,6 µg/ml. Hal tersebut menandakan jika daun alpukat dapat menjadi kandidat sebagai obat diabetes mellitus.

Keywords
Persea americana Mill, ekstrak etanol daun alpukat, α-amilase, antioksidan, akarbose.

Topic
Farmakologi dan Klinik TOOT

Link: https://ifory.id/abstract/3ceDEtBUgXx9

Corresponding Author
Nurrahmi Umami

Institutions
Conservative Department, Faculty of Dentistry, Muslim Indonesia University, Makassar,
Indonesia
Prosthodontic Department, Faculty of Dentistry, Muslim Indonesia University, Makassar,
Indonesia
Prosthodontic Department, Faculty of Dentistry, Hasanuddin University, Makassar,
Indonesia

Abstract
Abstract Objective: To analyze the difference of compressive strength between nanofilled composite resin and nanofilled composite resin reinforced with braided polyethylene fiber. Methods: Samples were made on pipette molds that are 10 mm in diameter and 10 mm in height. The first group contains only nanofilled composite resin. The second group contains nanofilled composite resin reinforced with braided polyethylene fiber. The samples were irradiated on a 2 mm layer for 20 seconds. The whole sample hardened, then incubated at 37oC for 1x24 hours. The samples then tested their compressive strength by using a universal testing machine. Statistical used independent sample t-test. Result: Compressive strength of nanofilled composite resin is 122.571 MPa and nanofilled composite resin reinforced with braided polyethylene fiber is 141.186 MPa, and based on statistical test determined p = 0.009 < p = 0.01. Conclusion: There was a difference of compressive strength between nanofilled composite resin and nanofilled composite resin reinforced with braided polyethylene fiber

Keywords
Nanofilled composite resin; Braided polyethylene fiber; Compressive strength

Topic
Information, technology, and women

Link: https://ifory.id/abstract/2Q8FwRDZACMn

Corresponding Author
Winda Rismayani

Institutions
(a) Departemen Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Institut Pertanian Bogor, Kampus IPB Dramaga, Bogor
(b) Departemen Statistika, Fakultas Matematika dan Ilmu Pengetahan Alam, Institut Pertanian Bogor

Abstract
Tempuyung (Sonchus arvensis L.) merupakan tanaman yang telah dimanfaatkan sebagai obat tradisional maupun sayuran di Indonesia. Daun tempuyung telah dilaporkan memiliki banyak khasiat, salah satunya sebagai antioksidan. Kandungan senyawa yang terkandung di dalam daun tempuyung dipengaruhi oleh beberapa faktor, salah satunya jenis dan pelarut pengekstraksi. Penelitian bertujuan menentukan korelasi antara gugus fungsi dan aktivitas antioksidan dari daun tempuyung dengan perbedaan jenis dan konsentrasi pelarut. Daun tempuyung diekstraksi dengan berbagai jenis dan konsentrasi pelarut, seperti akuades, etanol 10%, etanol 30%, etanol 50%, etanol 70%, dan etanol pa. Setiap ekstrak ditentukan aktivitas antioksidan, kadar fenolik total, dan gugus fungsi komponen ekstrak menggunakan spektrofotometer inframerah transformasi fourier (FTIR). Nilai aktivitas antioksidan dan kadar fenolik total tertinggi didapatkan pada ekstrak etanol 70%. Spektrum inframerah menghasilkan pola yang mirip, perbedaan hanya terdapat pada intensitasnya. Ekstrak daun tempuyung dapat dikelompokkan berdasarkan variasi pelarut pengekstraksi menggunakan kemometrika tipe principal component analysis (PCA) dengan total PC sebesar 93%. Data serapan gugus fungsi dikorelasikan dengan aktivitas antioksidan menggunakan partial least square (PLS). Hasil analisis PLS menunjukkan bahwa gugus fungsi –OH dan C-O merupakan gugus fungsi yang diduga berkontribusi paling tinggi pada aktivitas antioksidan ekstrak daun tempuyung.

Keywords
antioksidan, fenolik total, FTIR, PCA, PLS

Topic
Teknologi Panen dan Kontrol Kualitas

Link: https://ifory.id/abstract/hvDzwZr8xKG4

Corresponding Author
Nurrahmi Umami

Institutions
Periodontology Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Abstract
Abstract Objective: This systematic review was aimed to understand the management of endodontic-periodontic lesion. Methods: Pubmed and Wiley online searches were conducted to identify articles published in dental journals until April 2018. Manual searches of published full-text articles and related reviews were performed afterwards. Result: A total 16 studies were selected for inclusion, with 22 patients as subjects. All studies showed the decreased probing depth (PD) after treatment or healing of the lesion. All studies included were case report with treatment using root canal treatment (RCT) alone or RCT combination with bone graft or RCT with platelet rich fibrin (PRF). Conclusion: Treatment using root canal treatment (RCT) combination with bone graft was mostly used than the other treatment option in endo-perio lesion.

Keywords
Bone grafting; Endodontic-periodontic lesion; Endodontic treatment; Periodontitis

Topic
Communicable disease related to women

Link: https://ifory.id/abstract/643zrWMEVyJf

Corresponding Author
Hanni Prihhastuti Puspitasari

Institutions
1Departemen Farmasi Komunitas, Fakultas Farmasi, Universitas Airlangga, Surabaya
2Departemen Farmakognosi dan Fitokimia, Fakultas Farmasi, Universitas Airlangga, Surabaya

Abstract
Konsumsi herbal bukan merupakan hal asing bagi masyarakat Indonesia. Meski terbuat dari bahan alam, obat golongan ini berpotensi membahayakan apabila digunakan pada pasien penyakit kronis yang sedang mengkonsumsi obat modern/sintetis. Penelitian ini bertujuan untuk mengetahui penggunaan obat herbal pada pasien penyakit kronis. Untuk itu, dilakukan penelitian kualitatif dengan pendekatan studi kasus pada lima pasien hipertensi di Wilayah Surabaya yang diketahui pernah mengonsumsi obat herbal selain obat antihipertensi yang diperoleh dari resep dokter. Disamping memperoleh obat antihipertensi, tiga informan juga mendapatkan resep untuk penanganan kondisi kronis lain seperti diabetes mellitus dan dislipidemia. Tiga informan lebih memilih penggunaan ramuan tradisional demi pertimbangan jaminan keamanan karena jenis dan sumber bahan yang digunakan dapat diketahui. Dua informan lebih menyukai penggunaan produk jamu karena pertimbangan kepraktisan. Tiga informan telah mendiskusikan atau bahkan mendapatkan rekomendasi penggunaan herbal tersebut dari dokter yang meresepkan obat, sedangkan dua informan tidak pernah membicarakan dengan dokter karena kekuatiran akan larangan dokter. Semua informan menggunakan herbal bergantian dengan obat yang diresepkan dokter, kadang kala informan yang menggunakan herbal sebagai pengganti obat dokter. Dapat disimpulkan bahwa adanya penggunaan herbal pada pasien penyakit kronis tanpa pengawasan dokter dapat berpotensi membahayakan, terutama ketika ditujukan sebagai pengganti obat dari resep dokter.

Keywords
obat herbal, hipertensi, diabetes mellitus, dislipidemia

Topic
Farmasi Klinis dan Komunitas

Link: https://ifory.id/abstract/6uTNAczLZDCm

Corresponding Author
Nurrahmi Umami

Institutions
Conservative Department, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia.

Abstract
Abstract Objective: This study aims to investigate phosphate content which dissolves from tooth enamel after soaked with brown algae Padina sp extract. Method: Research type used is experimental research with pre and post-test group control design. Sample using maxillary first premolar that has separated crown and roots then planted with acrylic resin. Phosphate level test performed by an ascorbic acid method and then read the absorbance on UV-vis spectrophotometer. Result: Mean of value on Padina extract has no significant change (p>0.05), and positive control show significantly different (p<0.05). Conclusion: Brown algae Padina sp. more likely to be a material that inhibits the demineralization process so that this material is more potential as an applicative material

Keywords
Tooth enamel; Phosphate; Dental erosion; Padina sp

Topic
Occupational and women

Link: https://ifory.id/abstract/CEFhcKgwzL9A

Corresponding Author
Jaeyoung CHO

Institutions
Kyungpook National University

Abstract
New neutron detectors are being developed as demand for security applications increases. Li-containing single crystal has a significant results such as Cs2LiYCl6 (CLYC), Cs2LiLaBr6: Ce (CLLB) and LiI. Their performance of pulse shape discrimination of neutron/gamma makes it possible to detect neutron/gamma with a single material. However, there is difficulty such as material cost, handling, complexity and hygroscopic in crystal growth. In particular, CsI(Tl) crystal scintillator doesn-t have such difficulty with good scintillation performance. Therefore, we developed Li co-doped CsI(Tl) crystal scintillator for neutron detection. Thermal neutron detection is realized by the 6Li(n,t)α neutron capture reaction. The reaction products, an alpha particle and a triton, deposit a total of 4.8 MeV energy in the crystal. In this poster, Li co-doped CsI(Tl) single crystals have been studied with optical scintillation properties and neutron/gamma capabilities

Keywords
CsI(Tl), neutron detection,

Topic
Sensing materials and applications

Link: https://ifory.id/abstract/TnZKbA86EuUM

Corresponding Author
Syifa Muflihah

Institutions
Divisi Kimia Analitik, Departemen Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Institut Pertanian Bogor, Kampus IPB Dramaga, Bogor

Abstract
Sambiloto (Andrographis paniculata) mengandung diterpena lakton, salah satunya andrografolida sebagai zat aktif utama dari tanaman ini. Kandungan senyawa dalam sambiloto dapat dipengaruhi oleh beberapa faktor, salah satunya umur tanaman. Pelarut pengekstraksi juga akan mempengaruhi jumlah senyawa yang terekstraksi dalam tanaman. Umur tanaman yang digunakan, yaitu 2, 3, dan 4 bulan dengan pelarut pengekstraksi air dan etanol (50%, 70%, dan PA). Analisis dilakukan dengan metabolomik sidik jari menggunakan teknik spektroskopi ultraviolet-tampak (UV-Vis) dan inframerah (FTIR). Ekstrak herba sambiloto dengan perbedaan umur tanaman dan tipe pelarut pengekstraksi menghasilkan spektrum yang mirip, perbedaan hanya terdapat pada nilai absorbans. Setiap ekstrak diklasifikasikan menggunakan kemometrika tipe principal component analysis (PCA). Hasil PCA dari FTIR, UV-Vis, dan fusi data menunjukkan sampel dapat terkelompok dalam kelasnya masing-masing. Data FTIR lebih mendominasi hasil fusi data, karena data FTIR memiliki nilai eigen yang lebih besar dibandingkan data UV-Vis. Bi-plot PCA juga menunjukkan variabel yang berpengaruh pada klasifikasi fusi data adalah nilai absorbans yang dihasilkan dari FTIR.

Keywords
Fusi data, metabolomik sidik jari, PCA, sambiloto

Topic
Teknologi Panen dan Kontrol Kualitas

Link: https://ifory.id/abstract/t4yGXaKLunEr

Corresponding Author
ENNI SUKRIANI

Institutions
Hasanuddin University

Abstract
Ginger contains oleoresin and essential oils that can reduce the emesis of gravidarum in pregnancy. This research aims to determine the effect of giving ginger syrup on pregnant mothers to decrease the emesis gravidarum of the first trimester pregnant women. This study constituted quantitative research with quasi experiment. Design used was pretest-posttest. The samples in this research were 51 pregnant women divided into 3 groups, namely mothers who got ginger syrup, placebo, and motherrs who got B6. Implementation was carried out for 7 days. Data were analyzed using Chi Square,and Wilcoxon Test The results indicate the lowering of the frequency emesis gravidarum on the group given ginger syrup (p = 0,000), the group given placebo (p = 0.038), and the group given B6 (p = 0.003). The different mean value after 7 days of intervention are : Gingger syrup group (1.00 ± 0.00), Placebo group( 0.06 ± 0.01), and B6 group( 0.17 ± 0.1). The group given with ginger syrup is more effective to decrease the frequency of emesis gravidarum to the first trimester compared to B6 group and Placebo group.

Keywords
Ginger, Pregnant Women, Emesis Gravidarum

Topic
Herbal medicine

Link: https://ifory.id/abstract/tMgkQJEuDvCX

Corresponding Author
Nurdin Siregar

Institutions
Faculty of Mathematics and Natural Sciences
Medan State University
Email: nurdinfis[at]gmail.com

Abstract
Magnesium (Mg) doped ZnO Thin Film has been successfully synthesized using the sol-gel spin coating method. The materials was used in this research is zinc acetate dehydrate, magnesium, isopropanol and diethanolamine as the precursor material, doping, solvent and stabilizer. Magnesium (Mg) doped ZnO thin films with a variation of 0.5; 1,0; 1,5; 2.0 and 2.5% were deposited on the FTO conductive glass subtraction. The results of ZnO: Mg thin film characterization with XRD showed all hexagonal wurtize crystal structures with the smallest crystal size of 24 nm for 0.5% doping and 28 nm maximum for 2.5% Mg doping. The results of SEM characterization showed the morphology of ZnO: Mg thin films in the form of globular granules and almost uniform. The results of ZnO thin film characterization: with UV-Vis showed the greatest transmittance and absorbance values in the wavelength range of 350 nm to 400 nm.

Keywords
ZnO thin films, Magnesium (Mg), Sol-gel Spin Coating.

Topic
Nano-materials and applications

Link: https://ifory.id/abstract/HU6NhPL8Gtcd

Corresponding Author
Anila Impian Sukorini

Institutions
1Departemen Farmasi Komunitas, Fakultas Farmasi, Universitas Airlangga, Surabaya

Abstract
Penggunaan obat bahan alam oleh lansia dan anak-anak semakin meningkat, di sisi lain produksi dan distribusi obat bahan alam di Indonesia semakin marak. Penelitian ini bertujuan untuk mengidentifikasi penggunaan obat bahan alam oleh lansia dan anak-anak di Surabaya. Data dikumpulkan menggunakan kuesioner tentang jenis obat bahan alam dan tujuan penggunaannya. Responden adalah anggota posyandu lansia dan ibu dari anggota posyandu balita yang terpilih secara purposive. Jawaban responden selanjutnya diagregasikan dan disajikan dalam bentuk distribusi frekuensi. Sebanyak 232 responden (116 lansia dan 116 ibu dari balita) berpartisipasi sebagai responden secara sukarela. Hasil penelitian menunjukkan bahwa obat bahan alam digunakan oleh 74,1% lansia dan 50,9% anak-anak. Obat bahan alam lebih banyak digunakan oleh lansia sebagai upaya penyembuhan daripada pencegahan. Upaya penyembuhan yang dimaksud meliputi pengobatan untuk penyakit kronis (hipertensi, hiperkolesterolemia, hiperurisemia, dan diabetes). Enam produk jadi yang digunakan oleh responden teregistrasi sebagai jamu dan obat herbal terstandar. Satu produk yang digunakan oleh lansia merupakan produk yang ditarik ijin edarnya karena mengandung bahan kimia obat. Dapat disimpulkan bahwa responden lebih banyak menggunakan obat bahan alam dalam bentuk ramuan tradisional. Sebagian lansia menggunakan obat bahan alam sebagai terapi komplementer untuk penyakit kronis.

Keywords
obat bahan alam, lansia, anak

Topic
Farmasi Klinis dan Komunitas

Link: https://ifory.id/abstract/PycHevmrjMwD

Corresponding Author
Nurrahmi Umami

Institutions
Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia.
Department of Microbiology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.

Abstract
Abstract Tuberculosis verrucous cutis (TBVC) is a skin infection caused by Mycobacterium tuberculosis that occurred in the people who had been previously infected or immune to Mycobacterium tuberculosis. It is an acquired disease, characterized by the presence of a solitaire verrucous plaque, commonly seen on the hands and or feet and could present as a varies of different clinical morphologies. This case report presented three cases of TBVC that we found at Makassar Indonesia with various unique clinical manifestations. Mantoux test, histopathology characteristics and response to anti-tubercular therapy confirmed the diagnosis

Keywords
Anti-tuberculosis treatment; Clinical manifestation; Tuberculosis verrucosa cutis (TBVC)

Topic
Information, technology, and women

Link: https://ifory.id/abstract/XghMBDARWw7j